Karadeniz Ereğli State Hospital, Clinic of Ophthalmology, Zonguldak, Turkey
Celal Bayar University Faculty of Engineering, Department of Electrical and Electronics Engineering, Manisa, Turkey
Turk J Ophthalmol. 2020 Mar 5;50(1):44-49. doi: 10.4274/tjo.galenos.2019.40504.
The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed. Visual acuity, central foveal thickness, and cystoid lesion area percentage were used to evaluate treatment response. In the follow-up, there was a decrease in central foveal thicknesses and cystoid lesion area percentages in both eyes of 3 of the patients. However, 1 patient showed increases in both parameters. Visual acuity remained stable in 5 eyes and increased in 3 eyes. Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases.
本研究旨在报告 4 例诊断为后部小眼球的患者中，局部布林佐胺 1%治疗对视网膜劈裂样黄斑囊样水肿病变的疗效。回顾了 4 例临床诊断为后部小眼球的患者的病历，这些患者均开始接受局部布林佐胺 1%治疗。使用视力、中心凹视网膜厚度和囊样病变面积百分比来评估治疗反应。在随访中，3 例患者的双眼中心凹视网膜厚度和囊样病变面积百分比均有下降，而 1 例患者的这两个参数均增加。5 只眼的视力保持稳定，3 只眼的视力提高。局部布林佐胺治疗可能对某些情况下的黄斑囊样病变有一定的积极作用。
