Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, São Paulo, Brazil.
Menopause. 2020 Apr;27(4):450-458. doi: 10.1097/GME.0000000000001523.
This study aimed to investigate the prevalence of self-reported main pelvic floor disorders (PFD) (urinary incontinence [UI], pelvic organ prolapse [POP], and fecal incontinence [FI]) and its associated factors in women with premature ovarian insufficiency (POI) and a control group.
This was a cross-sectional study wherein two groups were interviewed from August, 2017 to November, 2018-women with POI (n = 150) and a control group matched for age and body weight (n = 150). Sociodemographic variables and two questionnaires validated in Brazilian Portuguese language for PFD (Kings Health Questionnaire [KHQ] and Pelvic Floor Distress Inventory-20 [PFDI-20]) were used. Laycock's power, endurance, repetitions, fast contractions, every contraction timed (PERFECT) scale for pelvic floor muscle assessment was used in both groups.
The prevalence of self-reported UI was 27.33% and 37.33% for POI and control groups (P > 0.05), respectively. There was no perceived difference regarding the prevalence of POP (9.33% POI group vs 8% control group; P = 0.682) and FI (8% POI vs 4% control group; P = 0.145). The P (power) (P = 0.46), E (endurance) (P = 0.91), R (repetitions) (P = 0.88), and F (fast contractions) (P = 0.19) values were statistically similar in both the groups. Multivariate analysis (n = 141) showed that higher weight (odds ratio [OR] 1.047 [1.018-1.076]; P < 0.001) and gravidity rates (OR 1.627 [1.169-2.266]; P < 0.01) were risk factors for UI and higher weight (OR 1.046 [1.010-1.084]; P = 0.01), and presence of comorbidities (OR 8.75 [1.07-71.44]; P < 0.01) were risk factors for POP in the POI group; there was no variable that was associated with FI.
Women with POI did not have significant differences when compared with the control group regarding the prevalence of PFD and pelvic floor muscle assessment. Having higher weight and gravidity rates were associated with self-reported UI, while the presence of comorbidities and higher weight were risk factors for POP in the POI group. : Video Summary:http://links.lww.com/MENO/A555.
本研究旨在调查患有卵巢早衰（POI）和对照组女性中自我报告的主要盆底功能障碍（PFD）（尿失禁[UI]、盆腔器官脱垂[POP]和粪便失禁[FI]）的患病率及其相关因素。
这是一项横断面研究，于 2017 年 8 月至 2018 年 11 月期间对两组进行了访谈 - POI 组（n=150）和年龄和体重匹配的对照组（n=150）。使用了社会人口统计学变量和两种经过巴西葡萄牙语验证的 PFD 问卷（Kings Health Questionnaire [KHQ]和 Pelvic Floor Distress Inventory-20 [PFDI-20]）。两组均使用 Laycock 力量、耐力、重复次数、快速收缩、每次收缩定时（PERFECT）评估盆底肌量表。
POI 组和对照组自我报告 UI 的患病率分别为 27.33%和 37.33%（P>0.05）。POP（POI 组 9.33%，对照组 8%；P=0.682）和 FI（POI 组 8%，对照组 4%；P=0.145）的患病率无差异。两组的 P（力量）（P=0.46）、E（耐力）（P=0.91）、R（重复次数）（P=0.88）和 F（快速收缩）（P=0.19）值均无统计学差异。多变量分析（n=141）显示，较高的体重（比值比[OR] 1.047 [1.018-1.076]；P<0.001）和生育次数（OR 1.627 [1.169-2.266]；P<0.01）是 UI 的危险因素，较高的体重（OR 1.046 [1.010-1.084]；P=0.01）和合并症的存在（OR 8.75 [1.07-71.44]；P<0.01）是 POI 组中 POP 的危险因素；没有与 FI 相关的变量。
与对照组相比，POI 组女性在 PFD 患病率和盆底肌评估方面无显著差异。较高的体重和生育次数与自我报告的 UI 相关，而合并症和较高的体重是 POI 组中 POP 的危险因素。
