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[Complete deficiency in the C2 fraction of complement associated with a glomerular nephropathy: apropos of 2 cases].

作者信息

Ayed K, Bardi R, Sassi F, Gorgi Y, Ben Maiz H, Haddad S, Ben Ayed H

机构信息

Laboratoire d'Immunologie, Faculté de Médecine de Tunis.

出版信息

Nephrologie. 1988;9(5):239-44.

PMID:3216945
Abstract

Two patients with non-systemic idiopathic glomerulonephritis were found to have a complete deficiency of C2, the second component of complement; the clinical course and serological abnormalities are reported in detail. An immunogenetic analysis of the patients of two families was carried out. It was demonstrated that the homozygous C2 deficiency was associated with homozygosity for HLA-A25-B18-DR2-BfS-C4A4-C4B2 haplotype.

摘要

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