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基底动脉直接支架置入术与支架置入术前球囊扩张术的安全性和中期效果比较。

Comparison of safety and mid-term effects between direct stenting and angioplasty before stenting in the basilar artery.

机构信息

Department of Neurology and Interventional Neurology, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao 266000, China.

Department of Neurology and Interventional Neurology, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao 266000, China.

出版信息

Clin Neurol Neurosurg. 2020 Jun;193:105773. doi: 10.1016/j.clineuro.2020.105773. Epub 2020 Mar 3.

Abstract

OBJECTIVES

Symptomatic atherosclerotic disease of the basilar artery (BA) portends a poor prognosis, and BA seemed to be the most dangerous site for stenting. The authors review their interventional results and mid-term results with or without predilation in BA stenting to find a safer interventional approach.

PATIENTS AND METHOD

A database review identified 94 patients with severe symptomatic BA stenosis were treated with stenting. According to with balloon predilation or not, they were divided into two groups: direct stenting group and angioplasty before stenting group. Baseline data, lesion characteristics, complications and follow-up data from the two groups were compared and analyzed.

RESULTS

The length of lesion in angioplasty before stenting group was longer than that in the direct stenting group (8.12 ± 2.76 mm versus 6.83 ± 2.27 mm, p = 0.015). The proportions of Mori C type lesion was higher in angioplasty before stenting group (31.3 % versus 8.7 %, p = 0.006). The residual stenosis was higher in angioplasty before stenting group (12.66 ± 9.24 % versus 7.67 ± 8.01 %, p = 0.006). There were no significant differences in TIA, stroke, and death between the two groups in the perioperative and postoperative > 1 year follow-up (p > 0.05).

CONCLUSION

BA stenting is relatively safe and has a good results for experienced operators. Angioplasty before stenting is a good way for BA stenting, it makes the operations on difficult lesions as safe as normal one. More optimized stents and safer interventional approach need to be further explored and verified.

摘要

目的

基底动脉(BA)有症状性动脉粥样硬化疾病预示着预后不良,BA 似乎是支架置入术最危险的部位。作者回顾了他们在 BA 支架置入术中进行或不进行预扩张的介入结果和中期结果,以寻找更安全的介入方法。

患者和方法

通过数据库回顾,确定了 94 例严重症状性 BA 狭窄患者接受支架置入术治疗。根据是否进行球囊预扩张,将他们分为两组:直接支架置入组和支架置入前血管成形组。比较并分析两组的基线数据、病变特征、并发症和随访数据。

结果

支架置入前血管成形组的病变长度长于直接支架置入组(8.12 ± 2.76 mm 比 6.83 ± 2.27 mm,p = 0.015)。支架置入前血管成形组 Mori C 型病变的比例更高(31.3%比 8.7%,p = 0.006)。支架置入前血管成形组残余狭窄率更高(12.66 ± 9.24%比 7.67 ± 8.01%,p = 0.006)。在围手术期和术后>1 年的随访中,两组间 TIA、中风和死亡的发生率无显著差异(p>0.05)。

结论

对于有经验的操作者来说,BA 支架置入术相对安全且效果良好。支架置入前血管成形术是一种很好的 BA 支架置入术方法,它使对困难病变的操作与正常病变一样安全。需要进一步探索和验证更优化的支架和更安全的介入方法。

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