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急性肾上腺功能不全作为经皮冠状动脉介入治疗后休克的神秘原因:心脏病专家的噩梦。

Acute adrenal insufficiency as a mysterious cause of shock following percutaneous coronary intervention: a cardiologist's nightmare.

作者信息

Kumar Barun, Kodliwadmath Ashwin, Singh Anupam, Duggal Bhanu

机构信息

Cardiology, All India Institute of Medical Sciences, Rishikesh, India.

Cardiology, All India Institute of Medical Sciences, Rishikesh, India

出版信息

BMJ Case Rep. 2020 Mar 12;13(3):e233585. doi: 10.1136/bcr-2019-233585.

Abstract

The differential diagnosis of shock following percutaneous coronary intervention (PCI) is vast. Access site complications and bleeding can cause hypovolemic shock. Peri-procedural myocardial infarction, abrupt closure, stent thrombosis, coronary dissection and coronary perforation have a stormy presentation. Vasovagal shock is manifested by bradycardia and hypotension and quickly responds to atropine. Anaphylactic shock secondary to contrast administration can be stormy but usually responds to steroids or adrenaline. Septicemia due to unsterile techniques can cause a less dramatic shock. Acute adrenal insufficiency causing shock following PCI has not been described to the best of our knowledge. We report the case of a 54-year-old woman who underwent successful multivessel PCI. She had refractory unexplained shock following the PCI with no much response from inotropic or intra-aortic balloon pump. After ruling out all possible causes of shock and clinical suspicion of adrenal insufficiency, she was treated with steroids resulting in dramatic improvement in her hemodynamics.

摘要

经皮冠状动脉介入治疗(PCI)后休克的鉴别诊断范围很广。穿刺部位并发症和出血可导致低血容量性休克。围手术期心肌梗死、急性闭塞、支架血栓形成、冠状动脉夹层和冠状动脉穿孔的表现凶险。血管迷走性休克表现为心动过缓和低血压,对阿托品反应迅速。造影剂所致的过敏性休克病情凶险,但通常对类固醇或肾上腺素反应良好。无菌技术操作不当导致的败血症可引起症状相对较轻的休克。据我们所知,尚未有关于PCI后因急性肾上腺功能不全导致休克的报道。我们报告一例54岁女性患者,其成功接受了多支血管PCI。PCI术后,她出现难治性不明原因休克,使用血管活性药物或主动脉内球囊反搏效果不佳。在排除所有可能的休克原因且临床怀疑肾上腺功能不全后,给予她类固醇治疗,其血流动力学状况显著改善。

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