• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

胸腔镜左肺癌肺叶切除术中连续术中神经监测在预防喉返神经损伤中的应用。

Application of Continuous Intraoperative Neuromonitoring During VATS Lobectomy for Left Lung Cancer to Prevent Recurrent Laryngeal Nerve Injury.

机构信息

Department of Surgery, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul, Korea.

Department of Anesthesiology and Pain Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul, Korea.

出版信息

Sci Rep. 2020 Mar 13;10(1):4636. doi: 10.1038/s41598-020-61500-6.

DOI:10.1038/s41598-020-61500-6
PMID:32170087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7069963/
Abstract

We applied continuous intraoperative neuromonitoring (CIONM) during video-assisted thoracoscopic surgery (VATS) lobectomy for left lung cancer and evaluated its safety and usefulness. An electrode was attached to a double-lumen tube, and placed at vocal cord level to detect the EMG signal evoked by vocal cord movement. Before 4 L lymph node dissection, an automatic periodic stimulation device was applied to the vagus nerve to stimulate vagus nerve continuously. Surgery was suspended if the amplitude decreased lower than the threshold and was resumed when the amplitude recovered. Ten patients (6 male, 4 female) were enrolled. CIONM was successfully performed in all patients without technical failure, and there was no hemodynamic instability. Amplitude decreased below the threshold in four patients. One patient did not recover amplitude and experienced transient vocal cord palsy. In the three other patients, the amplitude recovered above the threshold and no vocal cord palsy occurred. The six patients who did not exhibit amplitude decrease experienced no vocal cord palsy. Our results suggest that CIONM may be applied safely for VATS left lobectomy and may be used to predict postoperative vocal cord function. This approach may be helpful to prevent RLN injury during VATS left lobectomy.

摘要

我们在电视辅助胸腔镜手术(VATS)肺叶切除术中应用连续术中神经监测(CIONM),并评估其安全性和有效性。将电极连接到双腔管,并将其放置在声带水平以检测由声带运动引起的肌电图信号。在进行 4L 淋巴结清扫之前,应用自动周期性刺激装置对迷走神经进行连续刺激。如果振幅低于阈值,则暂停手术,当振幅恢复时恢复手术。共纳入 10 例患者(6 例男性,4 例女性)。所有患者均成功完成 CIONM,无技术故障,且血流动力学稳定。4 例患者的振幅低于阈值。1 例患者的振幅未恢复,出现短暂性声带麻痹。在其他 3 例患者中,振幅恢复至阈值以上,且未发生声带麻痹。未出现振幅下降的 6 例患者未发生声带麻痹。我们的结果表明,CIONM 可安全应用于 VATS 左肺叶切除术,并可用于预测术后声带功能。这种方法可能有助于预防 VATS 左肺叶切除术中 RLN 损伤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/b1d347c6a8a9/41598_2020_61500_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/7af68e763d68/41598_2020_61500_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/1d687f4c3cb6/41598_2020_61500_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/119c1dfea19f/41598_2020_61500_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/b1d347c6a8a9/41598_2020_61500_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/7af68e763d68/41598_2020_61500_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/1d687f4c3cb6/41598_2020_61500_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/119c1dfea19f/41598_2020_61500_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72e1/7069963/b1d347c6a8a9/41598_2020_61500_Fig4_HTML.jpg

相似文献

1
Application of Continuous Intraoperative Neuromonitoring During VATS Lobectomy for Left Lung Cancer to Prevent Recurrent Laryngeal Nerve Injury.胸腔镜左肺癌肺叶切除术中连续术中神经监测在预防喉返神经损伤中的应用。
Sci Rep. 2020 Mar 13;10(1):4636. doi: 10.1038/s41598-020-61500-6.
2
Adaptation of Continuous Intraoperative Vagus Nerve Stimulation for Monitoring of Recurrent Laryngeal Nerve During Minimally Invasive Esophagectomy.连续术中迷走神经刺激在微创食管切除术中用于监测喉返神经的适应性研究
World J Surg. 2016 Jan;40(1):137-41. doi: 10.1007/s00268-015-3265-4.
3
Impact of EMG Changes in Continuous Vagal Nerve Monitoring in High-Risk Endocrine Neck Surgery.肌电图变化在高危内分泌颈部手术连续迷走神经监测中的影响
World J Surg. 2016 Mar;40(3):672-80. doi: 10.1007/s00268-015-3368-y.
4
Continuous vagal intraoperative neuromonitoring during video-assisted thoracoscopic surgery for left lung cancer: its efficacy in preventing permanent vocal cord paralysis.在左侧肺癌的电视辅助胸腔镜手术中进行连续迷走神经术中神经监测:预防永久性声带麻痹的效果。
Interact Cardiovasc Thorac Surg. 2022 Nov 8;35(6). doi: 10.1093/icvts/ivac273.
5
Usefulness of intraoperative nerve monitoring in esophageal cancer surgery in predicting recurrent laryngeal nerve palsy and its severity.术中神经监测在食管癌手术中对预测喉返神经麻痹及其严重程度的作用。
Gen Thorac Cardiovasc Surg. 2019 Dec;67(12):1075-1080. doi: 10.1007/s11748-019-01107-5. Epub 2019 Mar 15.
6
Continuous vagal IONM prevents recurrent laryngeal nerve paralysis by revealing initial EMG changes of impending neuropraxic injury: a prospective, multicenter study.连续监测迷走神经可通过揭示即将发生的神经失用性损伤的初始肌电图变化来预防喉返神经麻痹:一项前瞻性、多中心研究。
Laryngoscope. 2014 Jun;124(6):1498-505. doi: 10.1002/lary.24550. Epub 2014 Feb 6.
7
Continuous intraoperative vagus nerve stimulation for identification of imminent recurrent laryngeal nerve injury.连续术中迷走神经刺激术识别即将发生的喉返神经损伤。
Head Neck. 2013 Nov;35(11):1591-8. doi: 10.1002/hed.23187. Epub 2012 Nov 20.
8
Continuous vagal monitoring value in prevention of vocal cord paralysis following thyroid surgery.甲状腺手术后预防声带麻痹中持续迷走神经监测值
Laryngoscope. 2018 Oct;128(10):2429-2432. doi: 10.1002/lary.27144. Epub 2018 Feb 26.
9
Postoperative vocal fold palsy in patients undergoing thyroid surgery with continuous or intermittent nerve monitoring.甲状腺手术中连续或间断神经监测患者的术后声带麻痹。
Br J Surg. 2015 Oct;102(11):1380-7. doi: 10.1002/bjs.9889. Epub 2015 Sep 2.
10
Safety and feasibility of a novel recurrent laryngeal nerve monitoring technique.一种新型喉返神经监测技术的安全性与可行性
Laryngoscope. 2018 Nov;128 Suppl 4:S1-S8. doi: 10.1002/lary.27282. Epub 2018 Oct 3.

引用本文的文献

1
Advances in vagus nerve management strategies in thoracoscopic lung resections: a narrative review.胸腔镜肺切除术中迷走神经管理策略的进展:一项叙述性综述
J Thorac Dis. 2025 Jul 31;17(7):5298-5308. doi: 10.21037/jtd-2024-2211. Epub 2025 Jul 18.
2
Recurrent Laryngeal Nerve Intraoperative Neuromonitoring Indications in Non-Thyroid and Non-Parathyroid Surgery.非甲状腺和非甲状旁腺手术中喉返神经术中神经监测的指征
J Clin Med. 2024 Apr 11;13(8):2221. doi: 10.3390/jcm13082221.
3
Continuous intraoperative neuromonitoring of the recurrent laryngeal nerve during lung operations.

本文引用的文献

1
Thoracoscopic lobectomy is a safe and versatile procedure: experience with 500 consecutive patients.电视胸腔镜肺叶切除术是一种安全且用途广泛的手术:500例连续患者的经验。
Ann Surg. 2006 Sep;244(3):420-5. doi: 10.1097/01.sla.0000234892.79056.63.
肺部手术期间对喉返神经进行术中连续神经监测。
J Thorac Dis. 2023 Aug 31;15(8):4198-4206. doi: 10.21037/jtd-22-1515. Epub 2023 Jul 13.
4
Surgical evaluation of station 4L in patients with lung cancer: the Ugly Duckling.肺癌患者4L站的外科评估:丑小鸭。
J Thorac Dis. 2023 Jan 31;15(1):14-16. doi: 10.21037/jtd-22-1448. Epub 2022 Dec 19.
5
Continuous vagal intraoperative neuromonitoring during video-assisted thoracoscopic surgery for left lung cancer: its efficacy in preventing permanent vocal cord paralysis.在左侧肺癌的电视辅助胸腔镜手术中进行连续迷走神经术中神经监测:预防永久性声带麻痹的效果。
Interact Cardiovasc Thorac Surg. 2022 Nov 8;35(6). doi: 10.1093/icvts/ivac273.
6
Impact on quality of life after vagus nerve and phrenic nerve guided systematic nodal dissection for non-small cell lung cancer patients: a prospective, single-arm clinical trial.迷走神经和膈神经引导下系统性淋巴结清扫术对非小细胞肺癌患者生活质量的影响:一项前瞻性单臂临床试验
Ann Transl Med. 2021 Dec;9(24):1753. doi: 10.21037/atm-21-5820.