Department of Surgery, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul, Korea.
Department of Anesthesiology and Pain Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul, Korea.
Sci Rep. 2020 Mar 13;10(1):4636. doi: 10.1038/s41598-020-61500-6.
We applied continuous intraoperative neuromonitoring (CIONM) during video-assisted thoracoscopic surgery (VATS) lobectomy for left lung cancer and evaluated its safety and usefulness. An electrode was attached to a double-lumen tube, and placed at vocal cord level to detect the EMG signal evoked by vocal cord movement. Before 4 L lymph node dissection, an automatic periodic stimulation device was applied to the vagus nerve to stimulate vagus nerve continuously. Surgery was suspended if the amplitude decreased lower than the threshold and was resumed when the amplitude recovered. Ten patients (6 male, 4 female) were enrolled. CIONM was successfully performed in all patients without technical failure, and there was no hemodynamic instability. Amplitude decreased below the threshold in four patients. One patient did not recover amplitude and experienced transient vocal cord palsy. In the three other patients, the amplitude recovered above the threshold and no vocal cord palsy occurred. The six patients who did not exhibit amplitude decrease experienced no vocal cord palsy. Our results suggest that CIONM may be applied safely for VATS left lobectomy and may be used to predict postoperative vocal cord function. This approach may be helpful to prevent RLN injury during VATS left lobectomy.
我们在电视辅助胸腔镜手术(VATS)肺叶切除术中应用连续术中神经监测(CIONM),并评估其安全性和有效性。将电极连接到双腔管,并将其放置在声带水平以检测由声带运动引起的肌电图信号。在进行 4L 淋巴结清扫之前,应用自动周期性刺激装置对迷走神经进行连续刺激。如果振幅低于阈值,则暂停手术,当振幅恢复时恢复手术。共纳入 10 例患者(6 例男性,4 例女性)。所有患者均成功完成 CIONM,无技术故障,且血流动力学稳定。4 例患者的振幅低于阈值。1 例患者的振幅未恢复,出现短暂性声带麻痹。在其他 3 例患者中,振幅恢复至阈值以上,且未发生声带麻痹。未出现振幅下降的 6 例患者未发生声带麻痹。我们的结果表明,CIONM 可安全应用于 VATS 左肺叶切除术,并可用于预测术后声带功能。这种方法可能有助于预防 VATS 左肺叶切除术中 RLN 损伤。