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弗雷氏手术联合胆道改道治疗慢性胰腺炎相关性胆道梗阻:改道类型的影响

Frey Procedure Combined with Biliary Diversion for the Treatment of Chronic Pancreatitis-Related Biliary Obstruction: Impact of the Types of Diversion.

作者信息

Ray Sukanta, Das Kshaunish, Jana Koustav, Das Roby, Kumar Dilip, Khamrui Sujan

机构信息

Division of Surgical Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, 244 A. J. C. Bose Road, Kolkata, West Bengal, 700020, India.

Division of Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, 244 A. J. C. Bose Road, Kolkata, West Bengal, 700020, India.

出版信息

World J Surg. 2020 Jul;44(7):2359-2366. doi: 10.1007/s00268-020-05465-7.

Abstract

BACKGROUND

Frey procedure (FP) has become the standard of treatment for patients with painful chronic pancreatitis and inflammatory head mass. Biliary diversion (BD) is necessary when there is persistent biliary obstruction after adequate head coring. The aim of the present study was to assess the impact of types of biliary diversion on short-term outcome and rates of stricture recurrence.

METHODS

All the patients, who underwent FP combined with BD between August 2007 and July 2017 in the Department of Surgical gastroenterology, Institute of Postgraduate Medical Education and Research, Kolkata, India, were retrospectively reviewed. The types of BD performed were choledochojejunostomy (Group A) or opening of the CBD in the resection cavity (Group B).

RESULTS

During the study period, 36 patients underwent FP with BD. Choledochojejunostomy was performed in 21 patients and opening of the CBD in the resection cavity in 15 patients. Preoperative characteristics and early surgical outcomes were comparable except the postoperative stay which was longer in those who underwent choledochojejunostomy (p = 0.044). Pain control was similar. Over a median follow-up of 72 months, five patients in the Group B developed stricture recurrence which was significantly higher than those of Group A (p = 0.008).

CONCLUSION

Choledochojejunostomy combined with FP achieves efficient BD with a lower rate of restricture compared with opening of the CBD in the resection cavity.

摘要

背景

Frey手术(FP)已成为疼痛性慢性胰腺炎和炎性头部肿块患者的治疗标准。当进行充分的头部去芯术后仍存在持续性胆道梗阻时,胆管改道(BD)是必要的。本研究的目的是评估胆管改道类型对短期结局和狭窄复发率的影响。

方法

回顾性分析2007年8月至2017年7月期间在印度加尔各答研究生医学教育与研究学院外科胃肠病科接受FP联合BD治疗的所有患者。所进行的BD类型为胆总管空肠吻合术(A组)或在切除腔内打开胆总管(B组)。

结果

在研究期间,36例患者接受了FP联合BD治疗。21例患者进行了胆总管空肠吻合术,15例患者在切除腔内打开了胆总管。术前特征和早期手术结局具有可比性,但接受胆总管空肠吻合术的患者术后住院时间更长(p = 0.044)。疼痛控制情况相似。在中位随访72个月期间,B组有5例患者出现狭窄复发,显著高于A组(p = 0.008)。

结论

与在切除腔内打开胆总管相比,胆总管空肠吻合术联合FP可实现有效的胆管改道,狭窄发生率更低。

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