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经颏下入路三孔内镜甲状旁腺切除术。

Endoscopic parathyroidectomy using a three-port submental approach.

机构信息

Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

出版信息

Langenbecks Arch Surg. 2020 Mar;405(2):241-246. doi: 10.1007/s00423-020-01861-8. Epub 2020 Mar 13.

Abstract

PURPOSE

The three-port submental endoscopic approach and its variations were introduced in 2016 and have been used for thyroidectomy since. However, there has been no report of this approach being used for parathyroidectomy [1, 2]. The objective of this paper was thus to report our experience using a three-port submental approach for endoscopic parathyroidectomy in challenging cases such as tertiary parathyroidism.

METHODS

We compared the outcomes before and after endoscopic removal of the parathyroid glands using a three-port submental endoscopic approach.

RESULTS

Endoscopic subtotal parathyroidectomy was performed using submental approach in five patients with tertiary hyperparathyroidism from January 2018 to June 2019. The parathyroid hormone levels of the patients dropped significantly after undergoing subtotal parathyroidectomy (mean difference 2260 pg/ml; 95% CI 1883.74 to 2636.65), as did calcium levels (mean difference 2.84 mg/dl; 95% CI 1.90 to 3.78). No major adverse events occurred in this study.

CONCLUSIONS

Submental approach parathyroidectomy allows for visualization of all parathyroid glands. Surgical scarring was minor and was hidden under the chin. The surgical outcomes were promising, and there were no major complications.

摘要

目的

三孔颏下入路内镜技术及其改良术式于 2016 年被引入甲状腺手术中,自此开始被用于甲状旁腺手术[1,2]。但目前尚无相关经此入路行甲状旁腺切除术的报道。因此,本文旨在报告我们在三孔颏下入路内镜甲状旁腺切除术治疗甲状旁腺癌等复杂病例中的经验。

方法

我们比较了经三孔颏下入路内镜甲状旁腺切除术前后的手术结果。

结果

2018 年 1 月至 2019 年 6 月,我们采用三孔颏下入路内镜技术对 5 例三发性甲状旁腺功能亢进症患者进行了内镜甲状旁腺次全切除术。术后甲状旁腺激素水平(平均差值 2260 pg/ml;95%CI 1883.74 至 2636.65)和血钙水平(平均差值 2.84 mg/dl;95%CI 1.90 至 3.78)均显著下降。本研究中未发生重大不良事件。

结论

颏下入路甲状旁腺切除术可以观察到所有甲状旁腺。手术瘢痕较小,隐藏在颏下。手术结果令人满意,且无重大并发症。

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