Department of Emergency Medicine, Medtigo Medical Group, North Adams, MA, USA.
Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Eur Heart J Qual Care Clin Outcomes. 2021 May 3;7(3):280-286. doi: 10.1093/ehjqcco/qcaa020.
Patients with heart failure (HF) have high costs, morbidity, and mortality, but it is not known if appropriate pharmacotherapy (AP), defined as compliance with international evidence-based guidelines, is associated with improved costs and outcomes. The purpose of this study was to evaluate HF patients' health care utilization, cost and outcomes in Region Halland (RH), Sweden, and if AP was associated with lower costs.
A total of 5987 residents of RH in 2016 carried HF diagnoses. Costs were assigned to all health care utilization (inpatient, outpatient, emergency department, primary health care, and medications) using a Patient Encounter Costing methodology. Care of HF patients cost €58.6 M, (€9790/patient) representing 8.7% of RH's total visit expenses and 14.9% of inpatient care (IPC) expenses. Inpatient care represented 57.2% of this expenditure, totalling €33.5 M (€5601/patient). Receiving AP was associated with significantly lower costs, by €1130 per patient (P < 0.001, 95% confidence interval 574-1687). Comorbidities such as renal failure, diabetes, chronic obstructive pulmonary disease, and cancer were significantly associated with higher costs.
Heart failure patients are heavy users of health care, particularly IPC. Receiving AP is associated with lower costs even adjusting for comorbidities, although causality cannot be proven from an observational study. There may be an opportunity to decrease overall costs and improve outcomes by improving prescribing patterns and associated high-quality care.
心力衰竭(HF)患者的医疗费用高、发病率和死亡率高,但尚不清楚适当的药物治疗(AP)——即符合国际循证指南——是否与降低成本和改善预后有关。本研究的目的是评估瑞典哈兰地区(RH)HF 患者的医疗保健利用、成本和结局,以及 AP 是否与降低成本有关。
2016 年,RH 共有 5987 名居民被诊断为 HF。使用患者就诊成本核算方法将所有医疗保健利用(住院、门诊、急诊、初级保健和药物治疗)的成本分配给每位患者。HF 患者的护理费用为 5860 万欧元(9790 欧元/患者),占 RH 总就诊费用的 8.7%,占住院治疗(IPC)费用的 14.9%。住院治疗占该支出的 57.2%,总计 3350 万欧元(5601 欧元/患者)。接受 AP 与成本显著降低相关,每位患者降低 1130 欧元(P<0.001,95%置信区间 574-1687)。合并症如肾衰竭、糖尿病、慢性阻塞性肺疾病和癌症与更高的成本显著相关。
心力衰竭患者是医疗保健的主要使用者,特别是 IPC。即使在调整合并症后,接受 AP 与降低成本相关,但不能从观察性研究中证明因果关系。通过改善处方模式和相关的高质量护理,可能有机会降低总体成本并改善预后。