iBET - Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal; LAQV-REQUIMTE/Department of Chemistry, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Caparica, Portugal.
Materials and Process Engineering, UCLouvain, Louvain-la-Neuve, Belgium.
J Hazard Mater. 2020 Jun 15;392:122330. doi: 10.1016/j.jhazmat.2020.122330. Epub 2020 Feb 19.
Anticancer drugs have been detected in the aquatic environment, they have a potent mechanism of action and their consumption is expected to drastically increase in the future. Consequently, it is crucial to routinely monitor the occurrence of anticancer drugs and to develop effective treatment options to avoid their release into the environment. Prior to implementing a monitoring program, it is important to define which anticancer drugs are more prone to be found in the surface waters. In this study the consumption of anticancer drugs in the Lisbon region (Portugal), Belgium and Haryana state (India) were used to estimate the concentrations that can be expected in surface waters. Moreover, one important aspect is to define the major entry route of anticancer drugs in the aquatic environment: is it hospital or household effluents? The results disclosed in this study showed that in Belgium and Lisbon, 94 % of the total amount of anticancer drugs were delivered to outpatients, indicating that household effluents are the primary input source of these drugs and thus, upgrading the treatment in the domestic wastewater facilities should be the focus.
在水生环境中已经检测到了抗癌药物，它们具有强大的作用机制，预计未来的消耗量将大幅增加。因此，定期监测抗癌药物的发生情况并开发有效的治疗方法以避免其释放到环境中至关重要。在实施监测计划之前，首先要确定哪些抗癌药物更容易在地表水中发现。在本研究中，使用了葡萄牙里斯本地区、比利时和印度哈里亚纳邦的抗癌药物消费数据来估计地表水中可能存在的浓度。此外，一个重要的方面是定义抗癌药物进入水生环境的主要途径：是医院还是家庭污水？本研究的结果表明，在比利时和里斯本，94%的抗癌药物总量是输送给门诊病人的，这表明家庭污水是这些药物的主要输入源，因此，应该将重点放在升级家庭废水处理设施的处理上。
