一名从古巴回国的旅行者因可能同时感染戊型肝炎而导致登革热并发肝功能障碍。

Dengue fever complicated by liver dysfunction due to possible co-infection with hepatitis E in a returning traveller from Cuba.

作者信息

Antinori Spinello, Morena Valentina, Pagani Gabriele, Venturi Giulietta, Giacomelli Andrea, Milazzo Laura, Ridolfo Anna Lisa, Zanchetta Nadia

机构信息

Department of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Italy; III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Milan, Italy.

National Reference Laboratory for Arboviruses, Department of Infectious Diseases, Istituto Superiore di Sanitá, Rome, Italy.

出版信息

Infez Med. 2020 Mar 1;28(1):98-103.

PMID:32172268

Abstract

Dengue fever is a mosquito-borne infection that co-circulates with Chikungunya and Zika virus infection in many parts of the world. Dengue virus (DENV) is occasionally responsible for acute hepatitis and a few cases of acute hepatitis due to co-infection with DENV and hepatitis E virus have been described in India. A 37-year-old Cuban woman living in Italy was admitted to our hospital with a presumed arboviral infection upon her return to Italy short after a 15-day trip to her home-country to visit relatives. An acute infection due to DENV serotype 1 was initially diagnosed, following a clinical course characterized by signs of liver dysfunction that were possibly due to co-infection with hepatitis E virus.

摘要

登革热是一种由蚊子传播的感染性疾病，在世界许多地区与基孔肯雅热和寨卡病毒感染共同流行。登革病毒（DENV）偶尔会引发急性肝炎，在印度已有数例因DENV与戊型肝炎病毒共同感染导致急性肝炎的病例报道。一名居住在意大利的37岁古巴女性，在回国探亲15天后返回意大利时，因疑似虫媒病毒感染入住我院。最初诊断为DENV 1型急性感染，其临床过程表现出肝功能障碍迹象，可能是由于与戊型肝炎病毒共同感染所致。