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胫骨平台骨折与长期死亡率升高相关:一项 7950 例患者的匹配队列研究。

Tibial plateau fractures are associated with a long-term increased risk of mortality: a matched cohort study of 7950 patients.

机构信息

Department of Orthopaedic Trauma Surgery, Aalborg University Hospital, 18-22 Hobrovej, 9000, Aalborg, Denmark.

Department of Occupational Therapy and Physiotherapy, Aalborg University Hospital, Aalborg, Denmark.

出版信息

Arch Orthop Trauma Surg. 2020 Nov;140(11):1705-1711. doi: 10.1007/s00402-020-03408-4. Epub 2020 Mar 14.

Abstract

INTRODUCTION

Disregarding proximal femoral fractures, the current literature includes only limited information regarding mortality following lower extremity fractures. Information regarding risk of mortality related to specific fracture patterns is essential when planning treatment modalities. The primary aim of this study was to report the long-term cumulative survival rate in patients with a tibial plateau fracture compared to an age- and gender-matched reference population.

MATERIALS AND METHODS

Patients who sustained a tibial plateau fracture in Denmark between 1996 and 2000 were included in the study. Survival status was monitored until 2015. We compared the mortality rate with a tenfold reference population matched on age and gender without a prior tibial plateau fracture. The study was based on register data from the Danish National Patient Register.

RESULTS

The study included 7950 patients sustaining 8065 tibial plateau fractures. The cohort had a mean follow-up period of 13.9 years. Patients with a tibial plateau fracture had a 1.52 (95% CI 1.46-1.58) times higher hazard ratio (HR) of death compared to the age- and gender-matched reference population. The 30-day, 6-month and 1-year mortality rates were 1.2%, 3.3% and 4.9%, respectively.

CONCLUSION

Patients with a proximal tibial plateau fracture have a higher cumulative risk of death during the mean 13.9-year observational period compared to an age- and gender-matched reference population.

摘要

简介

除了股骨近端骨折外,目前的文献仅包含关于下肢骨折后死亡率的有限信息。在制定治疗方案时,了解与特定骨折类型相关的死亡率风险的信息至关重要。本研究的主要目的是报告与年龄和性别匹配的参考人群相比,胫骨平台骨折患者的长期累积生存率。

材料和方法

本研究纳入了丹麦在 1996 年至 2000 年期间发生胫骨平台骨折的患者。对患者的生存状况进行了监测,直到 2015 年。我们将死亡率与 10 倍年龄和性别匹配且无胫骨平台骨折史的参考人群进行了比较。该研究基于丹麦国家患者登记处的登记数据。

结果

本研究纳入了 7950 例发生 8065 例胫骨平台骨折的患者。该队列的平均随访期为 13.9 年。与年龄和性别匹配的参考人群相比,胫骨平台骨折患者的死亡风险比为 1.52(95%CI 1.46-1.58)。30 天、6 个月和 1 年的死亡率分别为 1.2%、3.3%和 4.9%。

结论

在平均 13.9 年的观察期内,与年龄和性别匹配的参考人群相比,胫骨近端平台骨折患者的累积死亡风险更高。

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