Department of Orthopaedic Surgery, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Unit of Clinical Biostatistics, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Osteoarthritis Cartilage. 2019 May;27(5):805-809. doi: 10.1016/j.joca.2018.12.020. Epub 2019 Jan 8.
This study aims to investigate the risk of total knee replacement (TKR) following tibia plateau fractures. Secondary the study aims to investigate the risk of knee arthroscopy following tibial plateau fractures.
The study was designed as a matched cohort study. All patients who sustained a tibial plateau fracture in Denmark between January 1, 1996, and December 31, 2000, were included and followed until December 31, 2015. For each patient with a tibial plateau fracture, 10 matched citizens without a tibial plateau fracture were included as a reference group.
7,950 patients sustained a tibial plateau fracture in Denmark during the study period. The median age of patients was 52.6 (IQR: 32.4-71.5) years. The mean observational period was 13.9 years. 5.7% were treated with a TKR (N = 452), and 2.0% of patients from the reference group were treated with a TKR (N = 1,623). Patients with a tibial plateau fracture had a 3.5 (95%CI: 3.1-3.9) times higher hazard ratio (HR) compared to patients from the reference group. 7.6% of patients with a tibial plateau fracture were treated with a secondary knee arthroscopy (N = 603) and 2.0% of patients from the reference group were treated with a knee arthroscopy (N = 1,565). Patients with a tibial plateau fracture presented with a 5.0 (95%CI: 4.5-5.6)) times higher HR compared to patients in the reference group.
Tibial plateau fractures are associated with a 3.5 times increased risk of TKR compared with an age- and gender-matched reference group with a mean follow-up of 13.9 years.
本研究旨在探讨胫骨平台骨折后行全膝关节置换术(TKR)的风险。其次,本研究旨在探讨胫骨平台骨折后行膝关节镜检查的风险。
本研究设计为匹配队列研究。纳入 1996 年 1 月 1 日至 2000 年 12 月 31 日期间在丹麦发生胫骨平台骨折的所有患者,并随访至 2015 年 12 月 31 日。对于每例胫骨平台骨折患者,均纳入 10 名年龄和性别匹配、无胫骨平台骨折的公民作为对照组。
在研究期间,丹麦有 7950 例患者发生胫骨平台骨折。患者的中位年龄为 52.6(IQR:32.4-71.5)岁。平均观察期为 13.9 年。5.7%的患者接受了 TKR(N=452),对照组中有 2.0%的患者接受了 TKR(N=1623)。与对照组相比,胫骨平台骨折患者的危险比(HR)为 3.5(95%CI:3.1-3.9)倍。7.6%的胫骨平台骨折患者接受了二次膝关节镜检查(N=603),对照组中有 2.0%的患者接受了膝关节镜检查(N=1565)。与对照组相比,胫骨平台骨折患者的 HR 为 5.0(95%CI:4.5-5.6)倍。
与年龄和性别匹配的对照组相比,胫骨平台骨折患者在平均随访 13.9 年后行 TKR 的风险增加 3.5 倍。