Department of Gynecological Endocrinology, Poznan University of Medical Sciences, Poznan, Poland.
Department of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland.
Gynecol Endocrinol. 2020 Nov;36(11):959-967. doi: 10.1080/09513590.2020.1737006. Epub 2020 Mar 14.
fertilization can be considered as causative factor of increasing rate of multiple pregnancies. Analysis of factors contributing to reduction in the percentage of multiple pregnancies may contribute to overall improvement of ART results. We compared annual reports from The Australian and New Zealand Assisted Reproduction Database and US National Summary Reports presented by The Centers for Disease Control and Prevention. The aim of this study was to analyze results of ART outcomes in two countries presenting opposite approach to ART, particularly to number of transferred embryos and number of eSETs (elective single embryo transfers). We found significant increase in total number of initiated cycles and transfers with significant shift toward frozen cycles and transfers in both countries. Percentage of eSET increased while average number of embryos transferred per one transfer decreased significantly in both countries without significant difference between countries. We also noticed significant decrease in the rate of multiple pregnancies and percentage of pregnancies resulting in triplets in Australia with New Zealand. Decreasing number of multiple pregnancies and higher percentage of transfers and pregnancies resulting in singleton live birth are the changes in ART politics found in our analysis. United States of America have more significant changes toward eSET, although Australia and New Zealand have significantly higher percentage of eSET from the beginning of analysis.
受精可以被视为导致多胎妊娠率增加的原因之一。分析导致多胎妊娠率降低的因素可能有助于全面改善辅助生殖技术的结果。我们比较了来自澳大利亚和新西兰辅助生殖技术数据库的年度报告和美国疾病控制与预防中心提供的全国总结报告。本研究的目的是分析在对辅助生殖技术采取相反方法的两个国家的辅助生殖技术结果,特别是移植胚胎的数量和 eSET(选择性单胚胎移植)的数量。我们发现,两国的启动周期和移植数量都显著增加,冷冻周期和移植的比例也显著增加。两国的 eSET 百分比都有所增加,而每次移植的胚胎数量显著减少,但两国之间没有显著差异。我们还注意到,澳大利亚和新西兰的多胎妊娠率和三胞胎妊娠率显著下降。在我们的分析中,辅助生殖技术政策的变化是多胎妊娠率降低和单胎活产率更高的转移和妊娠。尽管美国在开始分析时就有了更显著的 eSET 转变,但澳大利亚和新西兰的 eSET 百分比明显更高。