Universidade Federal Da Paraíba, Cidade Universitária, 58051-085, João Pessoa, PB, Brazil; Núcleo De Pesquisa e Extensão, Laboratório De Combustíveis e Materiais (NPE -LACOM), Brazil.
Laboratório Interdisciplinar De Materiais Avançados (LIMAV), Centro De Tecnologia, Universidade Federal Do Piauí, Teresina, Piaui, 64064-260, Brazil.
Carbohydr Polym. 2020 May 15;236:116036. doi: 10.1016/j.carbpol.2020.116036. Epub 2020 Feb 20.
Diclofenac sodium (DS) is an emergent pollutant, and among the methods investigated for its removal, adsorption is the most widely utilized technique. Hydroxyapatite and chitosan are biomaterials often used for adsorption. However, both biomaterials are limited due to their low chemical stability in an acidic medium; furthermore, pure hydroxyapatite interacts poorly with diclofenac. In this work, hydroxyapatite was organofunctionalized with 3-aminopropyltrimethoxysilane and further used to obtain amino hydroxyapatite /chitosan hybrids by crosslinking with glutaraldehyde at pH 3, 4, 5, and 6. X-ray diffraction patterns indicated the preservation of the hydroxyapatite phase under all pH conditions. Based on the control reaction of the amino hydroxyapatite with glutaraldehyde and its further reduction in sodium borohydride, the formation of CN moieties was highlighted as the main interaction mechanism between the aldehyde and amino groups. Therefore, crosslinking with glutaraldehyde was evaluated by infrared, Raman spectroscopy, and C NMR techniques; the results suggested contributions of imine formation and hydrogen bonding. The hybrid obtained at pH 3 exhibited an enhanced adsorption capacity of 125 mg g at 15 min. The synergy between amino hydroxyapatite and chitosan crosslinked by glutaraldehyde was demonstrated.
双氯芬酸钠（DS）是一种新兴污染物，在研究的去除方法中，吸附是最广泛使用的技术。羟基磷灰石和壳聚糖是常用于吸附的生物材料。然而，由于它们在酸性介质中的化学稳定性低，这两种生物材料都受到限制；此外，纯羟基磷灰石与双氯芬酸的相互作用较差。在这项工作中，用 3-氨丙基三甲氧基硅烷对羟基磷灰石进行有机功能化，然后在 pH 值为 3、4、5 和 6 时用戊二醛交联进一步获得氨基羟基磷灰石/壳聚糖杂化体。X 射线衍射图谱表明在所有 pH 条件下都保持了羟基磷灰石相。基于氨基羟基磷灰石与戊二醛的对照反应及其在硼氢化钠中的进一步还原，突出了 CN 基团的形成作为醛和氨基之间的主要相互作用机制。因此，通过红外、拉曼光谱和 C NMR 技术评估了戊二醛的交联，结果表明形成了亚胺和氢键。在 pH 3 下获得的杂化物在 15 分钟时表现出增强的吸附容量为 125mg/g。证明了戊二醛交联的氨基羟基磷灰石和壳聚糖之间的协同作用。
