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初次单侧全髋关节置换术后出院后的阿片类药物使用:我们的处方是否过度?

Opioid Use After Discharge Following Primary Unilateral Total Hip Arthroplasty: How Much Are We Overprescribing?

机构信息

Hoag Orthopaedic Institute, Irvine, CA.

出版信息

J Arthroplasty. 2020 Jun;35(6S):S226-S230. doi: 10.1016/j.arth.2020.01.076. Epub 2020 Feb 1.

DOI:10.1016/j.arth.2020.01.076
PMID:32173620
Abstract

BACKGROUND

The opioid crisis pressures orthopedic surgeons to reduce the amount of narcotics prescribed for postoperative pain management. This study sought to quantify postoperative opioid use after hospital discharge for primary unilateral total hip arthroplasty (THA) patients.

METHODS

A prospective cohort of primary unilateral THA patients were enrolled at a single institution. Detailed pain journals tracked all prescription and over-the-counter pain medication, quantity, frequency, and visual analog scale pain scores. Pain medications were converted to morphine milligram equivalents (MME).

RESULTS

Data from 121 subjects were analyzed; the average visual analog scale pain score was 3.44 while taking narcotics. The average number of days taking narcotics was 8.46 days. The distribution of days taking narcotics was right shifted with 50.5% of patients off narcotics after 1 week, and 82.6% off by 2 weeks postoperatively. The average number of narcotic pills prescribed was significantly greater than narcotic pills taken (72.5 vs 28.8, P < .0001). The average MME prescribed was significantly greater than MME taken (452.1 vs 133.8, P < .0001). The average excess narcotic pills prescribed per patient was 51.7 pills. And 71.9% took fewer than 30 narcotic pills; 90.9% patients took fewer than 50 narcotic pills. Also, 10.7% did not require any narcotics; 9.9% required a refill of narcotics; and 33.1% went home the day of surgery.

CONCLUSION

Significantly more narcotics were prescribed than were taken in the postoperative period following THA with an average 51.7 excess narcotic pills per patient. Adjusting prescribing patterns to match patient narcotic usage could reduce the excess narcotic pills following THA.

摘要

背景

阿片类药物危机迫使矫形外科医生减少术后疼痛管理中开具的麻醉性镇痛药的数量。本研究旨在量化初次单侧全髋关节置换术(THA)患者出院后的术后阿片类药物使用量。

方法

在一家单机构前瞻性纳入了初次单侧 THA 患者的队列。详细的疼痛日记记录了所有处方和非处方止痛药的种类、数量、频率和视觉模拟评分。将止痛药转换为吗啡毫克当量(MME)。

结果

分析了 121 名受试者的数据;服用麻醉性镇痛药时平均视觉模拟评分(VAS)为 3.44。服用麻醉性镇痛药的平均天数为 8.46 天。服用麻醉性镇痛药的天数分布右移,50.5%的患者在术后 1 周后停用麻醉性镇痛药,82.6%在术后 2 周后停用。开的麻醉性镇痛药片数明显多于实际服用的片数(72.5 比 28.8,P<.0001)。开的 MME 明显多于实际服用的 MME(452.1 比 133.8,P<.0001)。每位患者平均多开 51.7 片麻醉性镇痛药。71.9%的患者服用的麻醉性镇痛药少于 30 片;90.9%的患者服用的麻醉性镇痛药少于 50 片。此外,10.7%的患者不需要任何麻醉性镇痛药;9.9%的患者需要麻醉性镇痛药的补充;33.1%的患者在手术当天出院。

结论

THA 术后患者服用的麻醉性镇痛药明显少于开具的麻醉性镇痛药,平均每位患者多开 51.7 片麻醉性镇痛药。调整开具麻醉性镇痛药的模式以匹配患者的麻醉性镇痛药使用量可能会减少 THA 术后的麻醉性镇痛药过量。

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