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比较产前子痫前期、产前持续产后子痫前期和新发性产后子痫前期患者的过程结局、临床症状和实验室值。

Comparison of process outcomes, clinical symptoms and laboratory values between patients with antepartum preeclampsia, antepartum with persistent postpartum preeclampsia, and new onset postpartum preeclampsia.

机构信息

Department of Obstetrics and Gynecology, Nassau University Medical Center, East Meadow, NY, USA.

Department of Obstetrics and Gynecology, Nassau University Medical Center, East Meadow, NY, USA; Department of Business Management, Brooklyn College, Brooklyn, NY, USA.

出版信息

J Gynecol Obstet Hum Reprod. 2020 May;49(5):101724. doi: 10.1016/j.jogoh.2020.101724. Epub 2020 Mar 12.

Abstract

OBJECTIVE

There is limited literature on postpartum preeclampsia for process outcomes, clinical symptoms, and laboratory values.

METHOD

Retrospective study comparing 3 groups of antepartum preeclampsia without postpartum preeclampsia (APNP; n = 43), antepartum preeclampsia with persistent postpartum preeclampsia (APYP; n = 59), and new onset postpartum preeclampsia (NEWYP; n = 18).

RESULTS

For process outcomes, NEWYP had higher odds for readmission as compared to APYP [OR: 5.41, 95 % CI: 1.34, 21.56, p = 0.02]. For clinical symptoms of postpartum highest systolic blood pressure NEWYP had greater values as compared to both APYP [B = 19.95, SE = 3.84, p < 0.001] and APNP [B = 23.63, SE = 2.87, p < 0.001]. For laboratory values of serum creatinine, NEWYP had greater values as compared to both APYP [B = 0.15, SE = 0.05, p = 0.01] and APNP [B = 0.17, SE = 0.05, p = 0.002].

CONCLUSION

NEWYP may represent a different disorder from APNP and APYP. We recommend close monitoring of NEWYP by clinicians.

摘要

目的

关于产后子痫前期的过程结局、临床症状和实验室值,相关文献有限。

方法

回顾性研究比较了 3 组无产后子痫前期的产前子痫前期患者(APNP;n=43)、持续产后子痫前期的产前子痫前期患者(APYP;n=59)和新发产后子痫前期患者(NEWYP;n=18)。

结果

在过程结局方面,与 APYP 相比,NEWYP 的再入院风险更高[比值比(OR):5.41,95%置信区间(CI):1.34-21.56,p=0.02]。在产后最高收缩压的临床症状方面,与 APYP 和 APNP 相比,NEWYP 的值更高[B=19.95,SE=3.84,p<0.001;B=23.63,SE=2.87,p<0.001]。在血清肌酐的实验室值方面,与 APYP 和 APNP 相比,NEWYP 的值更高[B=0.15,SE=0.05,p=0.01;B=0.17,SE=0.05,p=0.002]。

结论

NEWYP 可能与 APNP 和 APYP 代表不同的疾病。我们建议临床医生密切监测 NEWYP。

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