Department of Obstetrics and Gynecology, Nassau University Medical Center, East Meadow, NY, USA.
Department of Obstetrics and Gynecology, Nassau University Medical Center, East Meadow, NY, USA; Department of Business Management, Brooklyn College, Brooklyn, NY, USA.
J Gynecol Obstet Hum Reprod. 2020 May;49(5):101724. doi: 10.1016/j.jogoh.2020.101724. Epub 2020 Mar 12.
There is limited literature on postpartum preeclampsia for process outcomes, clinical symptoms, and laboratory values.
Retrospective study comparing 3 groups of antepartum preeclampsia without postpartum preeclampsia (APNP; n = 43), antepartum preeclampsia with persistent postpartum preeclampsia (APYP; n = 59), and new onset postpartum preeclampsia (NEWYP; n = 18).
For process outcomes, NEWYP had higher odds for readmission as compared to APYP [OR: 5.41, 95 % CI: 1.34, 21.56, p = 0.02]. For clinical symptoms of postpartum highest systolic blood pressure NEWYP had greater values as compared to both APYP [B = 19.95, SE = 3.84, p < 0.001] and APNP [B = 23.63, SE = 2.87, p < 0.001]. For laboratory values of serum creatinine, NEWYP had greater values as compared to both APYP [B = 0.15, SE = 0.05, p = 0.01] and APNP [B = 0.17, SE = 0.05, p = 0.002].
NEWYP may represent a different disorder from APNP and APYP. We recommend close monitoring of NEWYP by clinicians.
关于产后子痫前期的过程结局、临床症状和实验室值,相关文献有限。
回顾性研究比较了 3 组无产后子痫前期的产前子痫前期患者(APNP;n=43)、持续产后子痫前期的产前子痫前期患者(APYP;n=59)和新发产后子痫前期患者(NEWYP;n=18)。
在过程结局方面,与 APYP 相比,NEWYP 的再入院风险更高[比值比(OR):5.41,95%置信区间(CI):1.34-21.56,p=0.02]。在产后最高收缩压的临床症状方面,与 APYP 和 APNP 相比,NEWYP 的值更高[B=19.95,SE=3.84,p<0.001;B=23.63,SE=2.87,p<0.001]。在血清肌酐的实验室值方面,与 APYP 和 APNP 相比,NEWYP 的值更高[B=0.15,SE=0.05,p=0.01;B=0.17,SE=0.05,p=0.002]。
NEWYP 可能与 APNP 和 APYP 代表不同的疾病。我们建议临床医生密切监测 NEWYP。