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Deep Transcriptome Sequencing of Pediatric Acute Myeloid Leukemia Patients at Diagnosis, Remission and Relapse: Experience in 3 Malaysian Children in a Single Center Study.

作者信息

Osman Siti Hawa, Abu Nadiah, Aziz Habsah, Chow Yock Ping, Wan Mohamad Nazarie Wan Fahmi, Ab Mutalib Nurul-Syakima, Alias Hamidah, Jamal Rahman

机构信息

UKM Medical Molecular Biology Institute, The National University of Malaysia, Cheras, Malaysia.

Department of Pediatrics, UKM Medical Centre, Faculty of Medicine, The National University of Malaysia, Cheras, Malaysia.

出版信息

Front Genet. 2020 Feb 27;11:66. doi: 10.3389/fgene.2020.00066. eCollection 2020.

DOI:10.3389/fgene.2020.00066
PMID:32174960
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7056821/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4162/7056821/55bbe8734aa2/fgene-11-00066-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4162/7056821/55bbe8734aa2/fgene-11-00066-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4162/7056821/55bbe8734aa2/fgene-11-00066-g001.jpg

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Deep Transcriptome Sequencing of Pediatric Acute Myeloid Leukemia Patients at Diagnosis, Remission and Relapse: Experience in 3 Malaysian Children in a Single Center Study.小儿急性髓系白血病患者诊断、缓解和复发时的深度转录组测序：单中心研究中3名马来西亚儿童的经验
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[Allogenic transplantation of hematopoietic stem cells in the treatment of children with high-risk acute leukemia].异基因造血干细胞移植治疗儿童高危急性白血病
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本文引用的文献

1
Not Only Mutations Matter: Molecular Picture of Acute Myeloid Leukemia Emerging from Transcriptome Studies.并非只有突变起作用：转录组研究揭示的急性髓系白血病分子图景
J Oncol. 2019 Jul 30;2019:7239206. doi: 10.1155/2019/7239206. eCollection 2019.
2
Multi-study reanalysis of 2,213 acute myeloid leukemia patients reveals age- and sex-dependent gene expression signatures.对 2213 例急性髓系白血病患者的多研究重新分析揭示了年龄和性别依赖性的基因表达特征。
Sci Rep. 2019 Aug 27;9(1):12413. doi: 10.1038/s41598-019-48872-0.
3
Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
伴 t(8;21)的急性髓系白血病的基因组图谱和克隆进化：331 例患者的国际研究。
Blood. 2019 Mar 7;133(10):1140-1151. doi: 10.1182/blood-2018-05-852822. Epub 2019 Jan 4.
4
New approach for understanding genome variations in KEGG.KEGG 中基因组变异的新方法。
Nucleic Acids Res. 2019 Jan 8;47(D1):D590-D595. doi: 10.1093/nar/gky962.
5
Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome.采用全基因组、全外显子组和转录组三平台测序对癌症进行临床基因组分析。
Nat Commun. 2018 Sep 27;9(1):3962. doi: 10.1038/s41467-018-06485-7.
6
Gene expression profiling of acute myeloid leukemia samples from adult patients with AML-M1 and -M2 through boutique microarrays, real-time PCR and droplet digital PCR.通过 boutique 微阵列、实时 PCR 和液滴数字 PCR 对成人 AML-M1 和 -M2 急性髓细胞白血病样本进行基因表达谱分析。
Int J Oncol. 2018 Mar;52(3):656-678. doi: 10.3892/ijo.2017.4233. Epub 2017 Dec 28.
7
Pediatric AML: From Biology to Clinical Management.小儿急性髓系白血病：从生物学特性到临床管理
J Clin Med. 2015 Jan 9;4(1):127-49. doi: 10.3390/jcm4010127.
8
High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML.EVI1 和 MEL1 的高表达是小儿急性髓系白血病不良预后的一个有力标志。
Leukemia. 2015 May;29(5):1076-83. doi: 10.1038/leu.2015.5. Epub 2015 Jan 8.
9
The prognostic significance of early treatment response in pediatric relapsed acute myeloid leukemia: results of the international study Relapsed AML 2001/01.儿童复发性急性髓系白血病早期治疗反应的预后意义：国际研究复发性AML 2001/01的结果
Haematologica. 2014 Sep;99(9):1472-8. doi: 10.3324/haematol.2014.104182. Epub 2014 Apr 24.
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TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions.TopHat2：在存在插入、缺失和基因融合的情况下对转录组进行精确比对。
Genome Biol. 2013 Apr 25;14(4):R36. doi: 10.1186/gb-2013-14-4-r36.