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印度经导管主动脉瓣置换术的现状

Current status of transcatheter aortic valve replacement in India.

作者信息

Gupta Puneet, Arora Sameer, Qamar Arman, Gupta Mohit, Seth Ashok

机构信息

Department of Cardiology, Janakpuri Super Speciality Hospital, New Delhi, India.

Division of Cardiology, University of North Carolina, Chapel Hill, NC, USA.

出版信息

Cardiovasc Diagn Ther. 2020 Feb;10(1):83-88. doi: 10.21037/cdt.2019.05.04.

Abstract

Transcatheter aortic valve replacement (TAVR) has proven to be the cornerstone therapy for patients with severe aortic stenosis (AS). India is currently overburdened with AS, both rheumatic and non-rheumatic. Although TAVR has revolutionized the treatment of non-rheumatic AS it does offer a ray of hope for rheumatic AS in future. It is difficult to measure the actual burden of AS in India due to lack of epidemiological studies in this population. Variable estimates have been given indicating a large number of patients eligible for TAVR. Despite its enormous potential, TAVR is still beyond the reach of an average Indian citizen. The progress for TAVR in India remains rather slow with obstacles at multiple levels. These include high costs, lack of coverage by insurance companies, continuous ignorance in government policies, lack of sufficient trained TAVR performing operators and lack of healthcare providers trained in post-TAVR care. Additionally, unique anatomical factors such as smaller body surface area, smaller annulus size, low coronary ostia take-off, smaller calibre of iliac and common femoral arteries pose unique challenges in terms of need for smaller hardware and increased chances of complications. It is crucial that the policy makers and healthcare personnel wake up to the benefits of this innovation and take appropriate steps to ease the dissemination of TAVR across the country.

摘要

经导管主动脉瓣置换术(TAVR)已被证明是重度主动脉瓣狭窄(AS)患者的基石疗法。印度目前无论是风湿性还是非风湿性AS患者负担都过重。尽管TAVR彻底改变了非风湿性AS的治疗方式,但它确实为未来的风湿性AS治疗带来了一线希望。由于该人群缺乏流行病学研究,很难衡量印度AS的实际负担。已有不同的估计表明有大量患者适合接受TAVR治疗。尽管TAVR潜力巨大,但普通印度公民仍难以企及。印度TAVR的进展仍然相当缓慢,存在多个层面的障碍。这些障碍包括成本高昂、保险公司未提供保险覆盖、政府政策持续忽视、缺乏足够训练有素的TAVR手术操作人员以及缺乏接受过TAVR术后护理培训的医疗服务提供者。此外,独特的解剖因素,如较小的体表面积、较小的瓣环尺寸、较低的冠状动脉开口高度、较小的髂动脉和股总动脉管径,在需要更小的器械以及并发症几率增加方面带来了独特挑战。至关重要的是,政策制定者和医疗人员应认识到这项创新的益处,并采取适当措施促进TAVR在全国的推广。

相似文献

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Current status of transcatheter aortic valve replacement in India.印度经导管主动脉瓣置换术的现状
Cardiovasc Diagn Ther. 2020 Feb;10(1):83-88. doi: 10.21037/cdt.2019.05.04.

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