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大样本感音神经性听力损失成人患者耳鸣困扰的听力预测指标。

Audiometric Predictors of Bothersome Tinnitus in a Large Clinical Cohort of Adults With Sensorineural Hearing Loss.

机构信息

National Military Audiology and Speech Pathology Center, Walter Reed National Military Medical Center, Bethesda, Maryland.

Eaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary.

出版信息

Otol Neurotol. 2020 Apr;41(4):e414-e421. doi: 10.1097/MAO.0000000000002568.

Abstract

OBJECTIVE

To identify demographic and audiometric predictors of bothersome tinnitus within a large clinical cohort.

STUDY DESIGN

Retrospective chart review.

SETTING

Tertiary care hospital.

PATIENTS

51,989 English-speaking patients between 18 and 80 years of age that received initial audiometric evaluations at the Massachusetts Eye and Ear Infirmary between the years 2000 and 2016.

MAIN OUTCOME MEASURES

Patients were categorized according to whether or not tinnitus was the primary reason for their visit. The likelihood of tinnitus as a primary complaint (TPC) was evaluated as a function of age, sex, and audiometric configuration. Patient-reported tinnitus percepts were qualitatively assessed in relation to audiometric configuration.

RESULTS

Approximately 20% of adults who presented for an initial hearing evaluation reported TPC. The prevalence of TPC increased with advancing age until approximately 50 to 54 years, and then declined thereafter. In general, men were significantly more likely to report TPC than women. TPC was statistically associated with specific audiogram configurations. In particular, TPC was most prevalent for notched and steeply sloping hearing losses, but was relatively uncommon in adults with flat losses. Patients with frequency-restricted threshold shifts often reported tonal tinnitus percepts, while patients with asymmetric configurations tended to report broadband percepts.

CONCLUSIONS

The probability of seeking audiological evaluation for bothersome tinnitus is highest for males, middle-aged patients, and those with notched or high-frequency hearing losses. These findings support the theory that tinnitus arises from sharp discontinuities in peripheral afferent innervation and cochlear amplification, which may induce topographically restricted changes in the central auditory pathway.

摘要

目的

在大型临床队列中确定烦人的耳鸣的人口统计学和听力预测因素。

研究设计

回顾性图表审查。

设置

三级保健医院。

患者

2000 年至 2016 年间,在马萨诸塞眼耳医院接受初次听力评估的 51989 名 18 至 80 岁的讲英语患者。

主要观察指标

根据患者的耳鸣是否为就诊的主要原因,将患者分为两组。评估耳鸣作为主要主诉(TPC)的可能性与年龄、性别和听力配置有关。患者报告的耳鸣感知与听力配置相关进行定性评估。

结果

约 20%的成年初诊患者报告 TPC。TPC 的患病率随着年龄的增长而增加,直到大约 50 至 54 岁,然后下降。一般来说,男性报告 TPC 的可能性显著高于女性。TPC 与特定的听力图配置具有统计学关联。特别是,TPC 在有切迹和陡峭斜率的听力损失中最为常见,但在有平坦损失的成年人中相对罕见。有频率受限的阈值移位的患者经常报告音调耳鸣感知,而具有不对称配置的患者往往报告宽带感知。

结论

因烦人的耳鸣而寻求听力评估的概率在男性、中年患者和有切迹或高频听力损失的患者中最高。这些发现支持了耳鸣是由外周传入神经纤维和耳蜗放大的急剧不连续引起的理论,这可能导致中枢听觉通路的局部受限变化。

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