Bobby R. Alford Department of Otolaryngology - Head and Neck Surgery, Baylor College of Medicine.
Division of Otolaryngology, Department of Surgery, Texas Children's Hospital.
Otol Neurotol. 2020 Apr;41(4):444-451. doi: 10.1097/MAO.0000000000002555.
To analyze outcomes of cochlear implantation (CI) in prelingually-deafened, late-implanted patients.
A search of MEDLINE and EMBASE was performed in February 2018 using SCOPUS for the intersection of "cochlear implant," "prelingual," "deaf," and "delay."
Two independent reviewers screened all abstracts and titles for relevance, with conflicts resolved by either the primary or senior author. All articles passing this screen were subjected to a full-text review, during which the primary and senior author each examined manuscripts for inclusion and exclusion criteria. The Cochrane Risk of Bias Assessment Tool was used to assess potential sources of systematic error, and postoperative clinical outcomes were collected at the latest clinical follow-up.
Twenty-eight articles were yielded in the final systematic review, accounting for 542 patients. For open-set sentence scores, 10 studies representing 240 patients showed an overall estimated improvement of 44.6% (95% CI: 38.0-51.2%). In terms of quality of life, studies generally showed improvement when looking at specific emotional, social, or hearing-specific domains, but not in global measures. Nonuser rates ranged from 0 to 9.5%.
Despite performance that is generally poorer than what is generally seen in "traditional" candidates, prelingually-deafened, late-implanted (PL-LI) CI users can experience benefit in terms of both QOL and audiometric scores. The wide range of performance that is reported in the literature highlights the importance of careful patient counseling.
分析语前聋、延迟植入人工耳蜗患者的植入效果。
2018 年 2 月,通过 SCOPUS 在 MEDLINE 和 EMBASE 上进行了一次搜索,检索词为“耳蜗植入”、“语前”、“聋”和“延迟”。
两名独立的审查员筛选所有摘要和标题,以确定相关性,有争议的问题由主要或资深作者解决。通过这一筛选的所有文章都进行了全文审查,在此过程中,主要和资深作者都检查了纳入和排除标准的手稿。使用 Cochrane 偏倚风险评估工具评估潜在的系统误差来源,并在最新的临床随访中收集术后临床结果。
最终的系统评价产生了 28 篇文章,涉及 542 名患者。对于开放式句子评分,10 项研究代表 240 名患者,总体估计改善率为 44.6%(95% CI:38.0-51.2%)。在生活质量方面,研究通常在特定的情感、社会或听力特定领域显示出改善,但在全球衡量标准中没有改善。未使用者的比例从 0 到 9.5%不等。
尽管表现一般不如“传统”候选者,但语前聋、延迟植入(PL-LI)人工耳蜗使用者在生活质量和听力测量评分方面都可以受益。文献中报告的表现范围很广,强调了仔细的患者咨询的重要性。