From the Division of Pediatric Emergency Medicine, British Columbia Children's Hospital, Vancouver, British Columbia.
Division of Research Informatics, Children's Hospital Colorado, Aurora, Colorado.
Pediatr Infect Dis J. 2020 May;39(5):406-410. doi: 10.1097/INF.0000000000002586.
Viral acute respiratory tract infections (vARTI) are a frequent source of inappropriate antibiotic prescribing. We describe the prevalence of antibiotic prescribing for vARTI in the pediatric emergency department (ED) and urgent care (UC) within a health system, and identify factors associated with overall and broad-spectrum antibiotic prescribing.
Retrospective chart review within a single pediatric referral health system. Visits of patients, 3 months- 17 years old, with a discharge diagnosis of a vARTI from 2010 to 2015. Data collected included specific vARTI diagnosis, site type (ED or UC), provider type [pediatric emergency medicine subspecialist or physicians, nurse practitioners, physician assistants (non-PEM)] and discharge antibiotics. Odds ratios and 95% confidence intervals (CI) were calculated where appropriate.
There were 132,458 eligible visits, mean age 4.1 ± 4.3 years. Fifty-three percent were treated in an ED. Advanced practice providers, a term encompassing nurse practitioners and physician assistants, were the most common provider type (47.7%); 16.5% of patients were treated by a pediatric emergency medicine subspecialist. Antibiotics were prescribed for 3.8% (95% CI: 3.72-3.92) of children with vARTI; 25.4% (95% CI: 24.2-26.6) of these were broad-spectrum, most commonly first-generation cephalosporins (11%; 95% CI 10.2-11.9). Patients treated in an ED or by a non-PEM and those receiving chest radiograph (CXR) received antibiotics most frequently. Prescribing rates varied by specific vARTI diagnosis.
Patients discharged from the pediatric ED or UC with vARTI receive inappropriate antibiotics at a lower rate than reported in other community settings; however, they frequently receive broad-spectrum agents.
病毒急性呼吸道感染(vARTI)是不适当使用抗生素的常见原因。我们描述了在医疗系统内儿科急诊室(ED)和紧急护理(UC)中治疗 vARTI 的抗生素使用率,并确定了与总体和广谱抗生素使用相关的因素。
在单儿科转诊医疗系统中进行回顾性图表审查。2010 年至 2015 年期间,有 vARTI 出院诊断的 3 个月至 17 岁患者的就诊记录。收集的数据包括特定的 vARTI 诊断、就诊地点类型(ED 或 UC)、提供治疗的人员类型(儿科急诊医学专科医生或医生、执业护士、医师助理(非 PEM))和出院时使用的抗生素。在适当的情况下计算了比值比和 95%置信区间(CI)。
有 132458 例符合条件的就诊记录,平均年龄为 4.1±4.3 岁。53%的患者在 ED 接受治疗。高级实践提供者,包括执业护士和医师助理,是最常见的提供者类型(47.7%);16.5%的患者由儿科急诊医学专科医生治疗。3.8%(95%CI:3.72-3.92)的 vARTI 患儿使用了抗生素;其中 25.4%(95%CI:24.2-26.6)为广谱抗生素,最常见的是第一代头孢菌素(11%;95%CI 10.2-11.9)。在 ED 就诊或由非 PEM 治疗以及接受胸部 X 光检查(CXR)的患者最常使用抗生素。抗生素的使用与特定的 vARTI 诊断有关。
从儿科 ED 或 UC 出院的 vARTI 患儿使用抗生素的比例低于其他社区环境中报告的比例,但他们经常使用广谱药物。