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A scoping review of post opioid-overdose interventions.阿片类药物过量后干预措施的范围综述。
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Incidence of mortality due to rebound toxicity after 'treat and release' practices in prehospital opioid overdose care: a systematic review.院前阿片类药物过量护理中“治疗后释放”实践后反弹毒性导致死亡率的发生率:系统评价。
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Overdose Deaths Involving Opioids, Cocaine, and Psychostimulants - United States, 2015-2016.2015 - 2016年美国涉及阿片类药物、可卡因和精神兴奋剂的过量用药死亡情况
MMWR Morb Mortal Wkly Rep. 2018 Mar 30;67(12):349-358. doi: 10.15585/mmwr.mm6712a1.
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Post opioid overdose outreach by public health and public safety agencies: Exploration of emerging programs in Massachusetts.公共卫生和公共安全机构对阿片类药物过量的后续护理:马萨诸塞州新兴项目的探索。
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Acute Crisis Care for Patients with Mental Health Crises: Initial Assessment of an Innovative Prehospital Alternative Destination Program in North Carolina.心理健康危机患者的急性危机护理:北卡罗来纳州一项创新的院前替代目的地计划的初步评估。
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Patterns of health care utilization and cost before and after opioid overdose: findings from 10-year longitudinal health plan claims data.阿片类药物过量前后的医疗保健利用模式和成本:来自10年纵向健康计划索赔数据的发现
Subst Abuse Rehabil. 2017 Aug 16;8:57-67. doi: 10.2147/SAR.S135884. eCollection 2017.
7
Challenges and Opportunities to Engaging Emergency Medical Service Providers in Substance Use Research: A Qualitative Study.让紧急医疗服务提供者参与药物使用研究的挑战与机遇:一项定性研究
Prehosp Disaster Med. 2017 Apr;32(2):148-155. doi: 10.1017/S1049023X16001424. Epub 2017 Jan 26.
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Addiction. 2017 Feb;112 Suppl 2:12-22. doi: 10.1111/add.13656.
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Is a Prehospital Treat and Release Protocol for Opioid Overdose Safe?院前阿片类药物过量治疗与释放方案是否安全?
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10
Opioid Overdose History, Risk Behaviors, and Knowledge in Patients Taking Prescribed Opioids for Chronic Pain.服用处方类阿片治疗慢性疼痛患者的阿片类药物过量史、风险行为和相关知识。
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紧急医疗服务干预预防阿片类药物过量致死的机会。

Opportunities for Emergency Medical Services Intervention to Prevent Opioid Overdose Mortality.

作者信息

Barefoot Elizabeth H, Cyr Julianne M, Brice Jane H, Bachman Michael W, Williams Jefferson G, Cabanas Jose G, Herbert Kyle M

出版信息

Prehosp Emerg Care. 2021 Mar-Apr;25(2):182-190. doi: 10.1080/10903127.2020.1740363. Epub 2020 Apr 2.

DOI:10.1080/10903127.2020.1740363
PMID:32176548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7529698/
Abstract

The opioid crisis is a growing cause of mortality in the United States and may be mitigated by innovative approaches to identifying individuals at-risk of fatal opioid overdose. We examined Emergency Medical Services (EMS) utilization among a cohort of individuals who died from opioid overdose in order to identify potential opportunities for intervention. : Individuals who died of unintentional opioid overdose in a large North Carolina county between 01/01/2014 and 12/31/2016 were studied in a retrospective cohort. Death records obtained from North Carolina Vital Records were linked to EMS patient care records obtained from the county EMS System in order to describe the EMS encounters of each decedent in the year preceding their death. Patient demographics and EMS encounters were assessed to identify encounter characteristics that may be targeted for intervention. Chi-square tests and odds ratios were used to evaluate and characterize the statistical significance of differences in EMS utilization. : Of the 218 individuals who died from unintentional opioid overdose in the study interval, 30% (n = 66) utilized EMS in the year before their death and 17% (n = 38) had at least one EMS encounter with documented drug or alcohol use (i.e. "drug-related encounter"). The mean age at death was 38 (range 19-74) years, 30% were female, 89% were White, and 8% were Black/African American. Factors associated with higher incidence of EMS utilization included age (<.001), gender (=.006), and race (001). Decedents aged 56-65 had the highest EMS utilization (47%) and patients aged <25 and 25-35 had more drug-related EMS encounters (29% and 20%, respectively). The most common reasons for EMS utilization were "other medical" (27%), "non-traumatic pain" (20%), "traumatic injury" (16%), and "poisoning/drug ingestion" (14%). Drug or alcohol use was documented by EMS in 33% of all encounters and an opioid prescription was reported in 22% of encounters. Nearly one-third of individuals who died from accidental opioid overdose utilized EMS in the year before their death and nearly one-fifth had a drug-related encounter. EMS encounters may present an opportunity to identify individuals at-risk of opioid overdose and, ultimately, reduce overdose mortality.

摘要

阿片类药物危机在美国正日益成为导致死亡的一个原因,而通过创新方法识别有致命阿片类药物过量风险的个体或许可以缓解这一危机。我们研究了一组死于阿片类药物过量的个体的紧急医疗服务(EMS)使用情况,以便确定潜在的干预机会。在一个回顾性队列研究中,我们对2014年1月1日至2016年12月31日期间在北卡罗来纳州一个大县死于意外阿片类药物过量的个体进行了研究。从北卡罗来纳州生命记录处获得的死亡记录与从该县EMS系统获得的EMS患者护理记录相链接,以描述每个死者在其死亡前一年的EMS接触情况。评估患者人口统计学和EMS接触情况,以确定可能作为干预目标的接触特征。使用卡方检验和比值比来评估和描述EMS使用差异的统计学显著性。在研究期间死于意外阿片类药物过量的218名个体中,30%(n = 66)在死亡前一年使用了EMS,17%(n = 38)至少有一次记录有药物或酒精使用的EMS接触(即“与药物相关的接触”)。死亡时的平均年龄为38岁(范围19 - 74岁),30%为女性,89%为白人,8%为黑人/非裔美国人。与EMS使用发生率较高相关的因素包括年龄(<.001)、性别(=.006)和种族(=.001)。56 - 65岁的死者EMS使用率最高(47%),年龄<25岁和25 - 35岁的患者有更多与药物相关的EMS接触(分别为29%和20%)。EMS使用的最常见原因是“其他医疗”(27%)、“非创伤性疼痛”(20%)、“创伤性损伤”(16%)和“中毒/药物摄入”(14%)。在所有接触中,33%的接触有EMS记录的药物或酒精使用,22%的接触报告有阿片类药物处方。近三分之一死于意外阿片类药物过量的个体在死亡前一年使用了EMS,近五分之一有与药物相关的接触。EMS接触可能提供了一个识别有阿片类药物过量风险个体的机会,并最终降低过量死亡率。