Poddubnyĭ B K, Nechipaĭ A M, Kuvshinov Iu P, Efimov O N, Gubin A N
Ter Arkh. 1988;60(9):119-23.
The results of endoscopic diagnosis and case follow-up of 686 patients with precancerous gastric conditions usually identified as a risk group (chronic gastritis, polyps, peptic ulcer, conditions following distal stomach resections) have shown that in patients with symptoms of epithelial dysplasia of gastric mucosa indices of cancer detectability significantly exceeded those in similar pathological conditions without symptoms of epithelial dysplasia. They were 22.0 +/- 2.5% and 2.5 +/- 0.8%, respectively; indices of stage I stomach cancer detectability were 9.9 +/- 1.8% and 0.2 +/- 0.2%, respectively. Patients with precancerous stomach diseases with moderate and severe epithelial dysplasia found in their gastric biopsies, should be attributed to a risk group, and these changes of gastric mucosa must be regarded as the main criterion for the identification of such a group.
对686例通常被认定为风险组的胃癌前期疾病患者（慢性胃炎、息肉、消化性溃疡、远端胃切除术后情况）进行内镜诊断及病例随访的结果显示，胃黏膜上皮发育异常有症状的患者中癌症可检测性指标显著超过无上皮发育异常症状的类似病理状况患者。二者分别为22.0±2.5%和2.5±0.8%；I期胃癌可检测性指标分别为9.9±1.8%和0.2±0.2%。胃活检发现有中度和重度上皮发育异常的胃癌前期疾病患者应归为风险组，胃黏膜的这些变化必须被视为识别该组的主要标准。
