Choi Ji Young, Na Jung Im
Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi-do, Korea.
Indian J Dermatol. 2020 Mar-Apr;65(2):139-140. doi: 10.4103/ijd.IJD_191_18.
Childhood granulomatous periorificial dermatitis (CGPD) is a self-limiting skin condition characterized by papular eruptions around the mouth, nose and eyes of preadolescent children. We report two cases of intractable CGPD in which patients receiving growth hormone (GH) therapy showed persistent symptoms despite multiple treatment modalities. This association may suggest the role of GH in the pathogenesis of CGPD.
儿童肉芽肿性口周皮炎(CGPD)是一种自限性皮肤病,其特征为青春期前儿童的口、鼻和眼周围出现丘疹性皮疹。我们报告了两例难治性CGPD病例,尽管采用了多种治疗方式,但接受生长激素(GH)治疗的患者症状仍持续存在。这种关联可能提示生长激素在CGPD发病机制中的作用。