Kuwano Masumi, Nakao Tomohiro, Yonemoto Koji, Yamada Satoshi, Murayama Keitaro, Okada Kayo, Honda Shinichi, Ikari Keisuke, Tomiyama Hirofumi, Hasuzawa Suguru, Kanba Shigenobu
Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Nagasaki Support Center for Children, Women and People with Disabilities, Nagasaki, Japan.
Heliyon. 2020 Mar 6;6(3):e03527. doi: 10.1016/j.heliyon.2020.e03527. eCollection 2020 Mar.
Previous studies have reported clinical characteristics of hoarding disorder (HD), such as early onset, a chronic course, familiality, high unmarried rate, and high rates of comorbidities. However, clinical research targeting Japanese HD patients has been very limited. As a result, there is a low recognition of HD in Japan, leading to insufficient evaluation and treatment of Japanese HD patients. The aim of the current study was to delineate the clinical characteristics of Japanese HD patients. Thirty HD patients, 20 obsessive-compulsive disorder (OCD) patients, and 21 normal controls (NC) were targeted in this study. The HD group had a tendency toward higher familiality, earlier onset, and longer disease duration compared to the OCD group. In addition, the HD group showed a significantly higher unmarried rate than the NC group. The top two comorbidities in the HD group were major depressive disorder (56.7%) and attention-deficit/hyperactivity disorder (26.7%). The HD group had significantly higher scores on hoarding rating scales and lower scores on the Global Assessment of Functioning Scale than the other two groups. The current study showed a clinical trend in Japanese HD patients similar to previous studies in various countries, suggesting that HD may be a universal disease with consistent clinical symptoms.
以往的研究报告了囤积障碍（HD）的临床特征，如起病早、病程慢性、家族性、未婚率高以及共病率高。然而，针对日本HD患者的临床研究非常有限。因此，日本对HD的认知度较低，导致对日本HD患者的评估和治疗不足。本研究的目的是描述日本HD患者的临床特征。本研究纳入了30例HD患者、20例强迫症（OCD）患者和21例正常对照（NC）。与OCD组相比，HD组具有更高的家族性倾向、更早的起病年龄和更长的病程。此外，HD组的未婚率显著高于NC组。HD组最常见的两种共病是重度抑郁症（56.7%）和注意缺陷多动障碍（26.7%）。与其他两组相比，HD组在囤积评定量表上的得分显著更高，而在总体功能评定量表上的得分更低。本研究显示日本HD患者的临床趋势与各国以往的研究相似，表明HD可能是一种具有一致临床症状的普遍疾病。
