伴有高黏滞血症和梗阻性尿路病的γA骨髓瘤
Gamma A myeloma with hyperviscosity and obstructive uropathy.
作者信息
Roth R M, Glovsky M M, Cooper J F, Douglas S D
出版信息
J Urol. 1977 Apr;117(4):527-9. doi: 10.1016/s0022-5347(17)58521-3.
PMID:321814
Abstract
A patient with gamma A myeloma, hyperviscosity and an obstructive uropathy is described. Operation revealed a proteinaceous mass obstructing the right renal pelvis. Immunoprecipitin and immunofluorescent analysis of this mass and concentrated urine demonstrated the presence of gamma A myeloma protein, kappa light chains and albumin. This is the first description of an obstructive uropathy in multiple myeloma owing to a proteinaceous matrix containing paraprotein.
摘要
本文描述了一名患有γA骨髓瘤、高黏滞血症和梗阻性尿路病的患者。手术发现一个蛋白性肿块阻塞右肾盂。对该肿块及浓缩尿液进行免疫沉淀和免疫荧光分析，证实存在γA骨髓瘤蛋白、κ轻链和白蛋白。这是关于多发性骨髓瘤中因含副蛋白的蛋白性基质导致梗阻性尿路病的首次报道。
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