LKE red cell antigen and its relationship to P1 and Pk: serological study of a large family.

The fourth example of human anti-LKE was identified in the serum of an antenatal patient. Study of the red cells of the proband and her family confirmed the recessive inheritance of the LKE- phenotype. The blood groups of the family confirmed that Pk expression is greater on cells from LKE- members than on those from LKE+ members. In this family, the expression of LKE varied with the P1 phenotype. LKE- individuals occurred with an incidence of 0.0017 in the donor population of the Glasgow and West of Scotland Region.