Insunza A, de Pablo F, Croxatto H D, Letelier L M, Morante M, Croxatto H B
Servicio de Obstetricia y Ginecología, Hospital Sótero del Río, Puente Alto, Chile.
Acta Obstet Gynecol Scand. 1988;67(5):433-6. doi: 10.3109/00016348809004255.
Ectopic implantation of the embryo in the tube opposite to the ovary containing the corpus luteum constitutes evidence of peritoneal or uterine transmigration of the egg. The frequency of this phenomenon was reinvestigated utilizing histopathologic confirmation of the side of the corpus luteum. A tubal pregnancy contralateral to the ovulating ovary was found in 28% of 67 cases, indicating that either the oocyte, the zygote or the embryo had entered the tube in which implantation took place from a medial site such as the peritoneal or the uterine cavity rather than directly from the ovulating ovary. Assuming that once in the medial site there is equal chance of entering either tube, it follows that in 56% of tubal pregnancies the egg has entered the tube from a midline location. Attempts to recover the oocyte from the tubes in normal women were successful in fewer than 5% of cases contralateral to the corpus luteum. It is concluded that tubal pregnancy is associated with a significant increase in the occurrence of transmigration of the egg.
胚胎在与黄体所在卵巢相对侧的输卵管内着床，构成卵子经腹膜或子宫迁移的证据。利用对黄体所在侧的组织病理学确认，对这一现象的发生率进行了重新研究。在67例病例中，28%发现输卵管妊娠发生在与排卵卵巢相对侧，这表明卵母细胞、受精卵或胚胎是从诸如腹膜或子宫腔等内侧部位进入发生着床的输卵管，而非直接从排卵卵巢进入。假设一旦进入内侧部位，进入两侧输卵管的机会均等，那么在56%的输卵管妊娠中，卵子是从中线位置进入输卵管的。在正常女性中，从与黄体相对侧的输卵管中回收卵母细胞的尝试，成功的病例不到5%。结论是，输卵管妊娠与卵子迁移发生率的显著增加有关。
