Alsbirk P H
Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Denmark.
Acta Ophthalmol (Copenh). 1988 Oct;66(5):556-64. doi: 10.1111/j.1755-3768.1988.tb04380.x.
In an unselected population of 541 Greenland Eskimos, a survey was performed aiming at early primary angle-closure glaucoma (PACG) detection. Of the men 162/274 and women 182/267 were above the age of 40. The ophthalmological examination included slit-lamp grading of limbal chamber depth (LCD), axial Haag Streit pachymetric chamber depth (ACD) measurement and direct gonioscopy in all shallow chamber cases. Dark room prone position provocative tests were extensively used in suspects. In 3 men and 5 women PACG was diagnosed, giving, above age 40, a prevalence of 2% in men (3/162) and increasing the PACG prevalence to 10% in women (18/182) as 13 were known a priori. PACG suspects, needing prophylactical iridectomy or pilocarpine, constituted 1 man and 6 women. Furthermore, narrow angles were found in 14 men and 27 women above age 40, and so far untreated. On the present background of highly effective surgical and YAG-laser iridectomy facilities in early PACG, local, other arctic and global prevention of blindness aspects are briefly discussed, with a special outlook to SE-Asia.
在541名未经过挑选的格陵兰爱斯基摩人群体中，开展了一项旨在早期发现原发性闭角型青光眼（PACG）的调查。在这些人中，年龄超过40岁的男性有162/274人，女性有182/267人。眼科检查包括对所有浅前房病例进行角膜缘前房深度（LCD）的裂隙灯分级、使用Haag Streit光学相干生物测量仪测量轴向前房深度（ACD）以及直接房角镜检查。对于疑似病例，广泛采用暗室俯卧位激发试验。确诊为PACG的男性有3人，女性有5人，40岁以上男性的患病率为2%（3/162），由于事先已知13例，女性PACG患病率升至10%（18/182）。需要进行预防性虹膜切除术或使用毛果芸香碱治疗的PACG疑似病例，男性有1人，女性有6人。此外，在40岁以上的14名男性和27名女性中发现了窄房角，且尚未接受治疗。基于目前早期PACG有高效的手术和YAG激光虹膜切除术治疗手段，本文简要讨论了当地、北极其他地区以及全球范围内预防失明的相关问题，并特别关注了东南亚地区。
