Maheshwari Sagar, Patil Monica, Shendey Shweta
Department of Radiodiagnosis, B J Govt. Medical College & Sassoon General Hospitals, Pune, India.
J Radiol Case Rep. 2019 Oct 31;13(10):1-10. doi: 10.3941/jrcr.v13i10.3671. eCollection 2019 Oct.
Mucormycosis is a rare opportunistic fungal infection, often life-threatening. We report an unusual case of rhinocerebral mucormycosis in an immunocompetent patient. A 23-year-old male presented with headache, speech disturbance and hearing difficulty for 4 weeks. Magnetic resonance imaging (MRI) revealed right cerebellar abscess and enhancing soft tissue in the nasal cavity, extending to cranial and infratemporal fossae. Computed tomography (CT) revealed the widening of foramen rotundum and sclerosis involving the sphenoid and ethmoid sinuses. MR Spectroscopy revealed multiple peaks between 3.6 and 3.8 parts per million (ppm) which could represent trehalose. Nasal mucosa scrapings confirmed mucormycosis. Suspicion of a fungal infection needs to be considered even in the absence of immunocompromised status.
毛霉菌病是一种罕见的机会性真菌感染，常危及生命。我们报告一例免疫功能正常患者发生的不寻常的鼻脑型毛霉菌病病例。一名23岁男性出现头痛、言语障碍和听力困难4周。磁共振成像（MRI）显示右侧小脑脓肿以及鼻腔内强化软组织，延伸至颅窝和颞下窝。计算机断层扫描（CT）显示圆孔增宽以及蝶窦和筛窦骨质硬化。磁共振波谱显示在百万分之3.6至3.8（ppm）之间有多个峰，可能代表海藻糖。鼻黏膜刮片确诊为毛霉菌病。即使在没有免疫功能低下状态的情况下，也需要考虑真菌感染的可能性。
