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大手术中延长半衰期重组凝血因子IX——如何改善临床实践:个体内比较

Extended half-life rFIX in major surgery-How to improve clinical practice: An intraindividual comparison.

作者信息

Valeri Federica, Agnelli Giacchello Jacopo, Dainese Cristina, Valpreda Alessandra, Montaruli Barbara, Dosio Enrico, Boccadoro Mario, Borchiellini Alessandra

机构信息

Haematology Unit Regional Center for Hemorrhagic and Thrombotic Diseases City of Health and Science University Hospital of Molinette Turin Italy.

Regional Center for Hemorrhagic and Thrombotic Diseases Haematology Laboratory City of Health and Science University Hospital of Molinette Turin Italy.

出版信息

Clin Case Rep. 2020 Feb 12;8(3):531-534. doi: 10.1002/ccr3.2450. eCollection 2020 Mar.

Abstract

Practical, safe, and effective hemostatic approach to orthopedic surgery using Extended Half-Life factor IX in hemophilia B. By intraindividual comparison, we found a lower FIX consumption, number of infusions, and cost compared to plasma-derived FIX.

摘要

在乙型血友病中使用延长半衰期的凝血因子IX进行骨科手术的实用、安全且有效的止血方法。通过个体内比较,我们发现与血浆源性凝血因子IX相比,凝血因子IX的消耗量、输注次数和成本更低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/7069879/ee52d4e44288/CCR3-8-531-g001.jpg

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