Department of Epidemiology, University of Washington, Seattle, Washington, USA.
Seattle Children's Research Institute, Seattle, Washington, USA.
J Pediatric Infect Dis Soc. 2021 Mar 26;10(2):183-187. doi: 10.1093/jpids/piaa023.
We applied whole genome sequencing to identify putative transmission clusters among clinical multidrug-resistant Escherichia coli sequence type 131-H30 isolates from 4 United States children's hospitals. Of 126 isolates, 17 were involved in 8 putative transmission clusters; 4 clusters showed evidence of healthcare-associated epidemiologic linkages. Geographic clustering analyses showed weak geographic clustering.
我们应用全基因组测序来鉴定来自美国 4 家儿童医院的临床多重耐药大肠杆菌 131-H30 序列型分离株之间的可能传播集群。在 126 株分离株中,17 株涉及 8 个可能的传播集群;4 个集群显示出与医疗保健相关的流行病学联系的证据。地理聚类分析显示出较弱的地理聚类。