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牙髓电刺激后牙髓血流量的变化——辣椒素和胍乙啶的影响

Changes in dental blood flow following electrical tooth pulp stimulation--influences of capsaicin and guanethidine.

作者信息

Raab W H, Magerl W, Müller H

机构信息

Universität Erlangen, FRG.

出版信息

Agents Actions. 1988 Dec;25(3-4):237-9. doi: 10.1007/BF01965022.

DOI:10.1007/BF01965022
PMID:3218601
Abstract

The responses of rat incisors microcirculation to electrical pulp stimulation was examined. A fast initial decrease was followed by a long lasting increase in blood flow due to activation of sympathetic efferents and nociceptive afferents, respectively. Both constituents of the response could be abolished differentially by the use of guanethidine (sympathectomy) and capsaicin (C-deafferentiation), respectively. The results point to a role of both C-efferents and peptidergic C-afferents in the control of tooth pulp circulation.

摘要

研究了大鼠切牙微循环对牙髓电刺激的反应。由于交感传出神经和伤害性传入神经的激活,血流先出现快速的初始下降,随后是持续较长时间的增加。分别使用胍乙啶(交感神经切除术)和辣椒素(C类传入神经去传入作用)可分别差异性地消除反应的这两种成分。结果表明C类传出神经和肽能C类传入神经在牙髓循环控制中均起作用。

相似文献

1
Changes in dental blood flow following electrical tooth pulp stimulation--influences of capsaicin and guanethidine.牙髓电刺激后牙髓血流量的变化——辣椒素和胍乙啶的影响
Agents Actions. 1988 Dec;25(3-4):237-9. doi: 10.1007/BF01965022.
2
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本文引用的文献

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Blood flow changes in the dental pulp of the cat and rat measured simultaneously by laser Doppler flowmetry and local 125I clearance.通过激光多普勒血流仪和局部¹²⁵I清除率同步测量猫和大鼠牙髓中的血流变化。
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