Department of Neurology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Department of Gerontology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
J Tradit Chin Med. 2019 Feb;39(1):97-102.
To investigate neuropsychological features of post-stroke cognitive impairment with no dementia (PSCIND) patients with different Traditional Chinese Medicine (TCM) syndromes.
We recruited 50 patients with PSCIND between April 2012 and March 2013. Patients were divided into different groups according to TCM classifications. Patients were assessed using neuropsychological tests, including cognitive screening (mini-mental state examination), memory testing (auditory verbal learning test), executive/attention [shape trails test, stroop color-word test (SCWT), reading the mind in the eyes test, the digit ordering test-A (DOT-A), and symbol digit modalities test], language (action naming test, Boston naming test, famous face test, similarity test, and verbal fluency test), and visuospatial functioning [complex figure test (CFT)].
We found no significant differences between patients with and without a diagnosis of turbid phlegm blocking the upper orifices on neuropsychological test performance. Patients diagnosed with upper hyperactivity of liver Yang syndrome scored significantly lower on the SCWT-C executive test and the CFT-delayed recall memory test. Patients with excess syndrome scored significantly lower on the SCWT-C executive test, and significantly higher on the DOT-A executive test.
Neuropsychological characteristics differ between PSCIND patients with different TCM classifications.
探讨不同中医证型的卒中后认知障碍非痴呆（PSCIND）患者的神经心理学特征。
我们招募了 2012 年 4 月至 2013 年 3 月期间的 50 名 PSCIND 患者。根据中医分类将患者分为不同组。使用神经心理学测试对患者进行评估，包括认知筛查（简易精神状态检查）、记忆测试（听觉词语学习测试）、执行/注意力[形状轨迹测试、斯特鲁普色词测试（SCWT）、读心于眼测试、数字排序测试-A（DOT-A）和符号数字模式测试]、语言[动作命名测试、波士顿命名测试、名人面孔测试、相似性测试和言语流畅性测试]和视空间功能[复杂图形测试（CFT）]。
我们发现有或没有痰浊阻窍诊断的患者在神经心理学测试表现上没有显著差异。被诊断为肝阳上亢的患者在 SCWT-C 执行测试和 CFT 延迟回忆记忆测试中的得分显著较低。有实证的患者在 SCWT-C 执行测试中得分显著较低，而在 DOT-A 执行测试中得分显著较高。
不同中医证型的 PSCIND 患者的神经心理学特征存在差异。
