在冷水浸泡过程中，血液浓缩而非体温降低会增加血液黏稠度。
Haemoconcentration, not decreased blood temperature, increases blood viscosity during cold water immersion.
作者信息
Rostomily Kaitlyn A, Jones Douglas M, Pautz Carina M, Ito Danica W, Buono Michael J
机构信息
San Diego State University, San Diego CA, USA.
Corresponding author: Dr Michael J Buono, MC-7251, San Diego State University, San Diego, CA 92182, USA,
出版信息
Diving Hyperb Med. 2020 Mar 31;50(1):24-27. doi: 10.28920/dhm50.1.24-27.
INTRODUCTION
Prolonged cold-water immersion (CWI) has the potential to cause significant hypothermia and haemoconcentration; both of which have previously been shown to independently increase blood viscosity in vitro. The purpose of this study was to determine the effect of CWI on blood viscosity and examine the relative contribution of decreased blood temperature and haemoconcentration.
METHODS
Ten healthy volunteers were immersed to mid-sternum in 10°C water for 90 minutes. Gastrointestinal (GI) temperature, haematocrit (Hct), and blood viscosity were measured pre- and post-CWI.
RESULTS
CWI caused mean (SD) GI temperature to decrease from 37.5 (0.3)°C to 36.2 (0.7)°C (P < 0.05). CWI also caused mean Hct to increase from 40.0 (3.5)% to 45.0 (2.9)% (P < 0.05). As a result of the haemoconcentration and decreased GI temperature during CWI the mean blood viscosity increased by 19% from 2.80 (0.28) mPa·s⁻¹ to 3.33 (0.42) mPa·s⁻¹ (P < 0.05). However, when the pre-CWI blood sample was measured at the post-CWI GI temperature (36.2°C) there was no significant difference in the blood viscosity when compared to the pre-CWI (37.5°C) blood sample (2.82 (0.20) mPa·s-1 and 2.80 (0.28) mPa·s-1 respectively). Furthermore, the changes in Hct and blood viscosity during CWI were significantly correlated with an r = 0.84.
CONCLUSION
The results of the current study show that prolonged, severe CWI causes a significant 19% increase in blood viscosity. In addition, the results strongly suggest that almost all of the increased blood viscosity seen following CWI is the result of haemoconcentration, not decreased blood temperature.
引言
长时间冷水浸泡（CWI）有可能导致显著的体温过低和血液浓缩；此前已表明这两者在体外均可独立增加血液粘度。本研究的目的是确定CWI对血液粘度的影响，并研究体温降低和血液浓缩的相对作用。
方法
10名健康志愿者浸入10°C水中至胸骨中部，持续90分钟。在CWI前后测量胃肠道（GI）温度、血细胞比容（Hct）和血液粘度。
结果
CWI导致平均（标准差）GI温度从37.5（0.3）°C降至36.2（0.7）°C（P < 0.05）。CWI还导致平均Hct从40.0（3.5）%增加到45.0（2.9）%（P < 0.05）。由于CWI期间的血液浓缩和GI温度降低，平均血液粘度从2.80（0.28）mPa·s⁻¹显著增加19%至3.33（0.42）mPa·s⁻¹（P < 0.05）。然而，当在CWI后的GI温度（36.2°C）下测量CWI前的血液样本时，与CWI前（37.5°C）的血液样本相比，血液粘度无显著差异（分别为2.82（0.20）mPa·s⁻¹和2.80（0.28）mPa·s⁻¹）。此外，CWI期间Hct和血液粘度的变化显著相关，r = 0.84。
结论
本研究结果表明，长时间、严重的CWI会导致血液粘度显著增加19%。此外，结果强烈表明，CWI后所见的几乎所有血液粘度增加都是血液浓缩的结果，而非体温降低。
Zotero 插件