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基于随机转移模型的日本 COVID-19 感染传播分析。

Analysis of COVID-19 infection spread in Japan based on stochastic transition model.

机构信息

Department of Human and Engineered Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.

Institute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.

出版信息

Biosci Trends. 2020 May 21;14(2):134-138. doi: 10.5582/bst.2020.01482. Epub 2020 Mar 19.

Abstract

To assess the effectiveness of response strategies of avoiding large gatherings or crowded areas and to predict the spread of COVID-19 infections in Japan, we developed a stochastic transmission model by extending the Susceptible-Infected-Removed (SIR) epidemiological model with an additional modeling of the individual action on whether to stay away from the crowded areas. The population were divided into three compartments: Susceptible, Infected, Removed. Susceptible transitions to Infected every hour with a probability determined by the ratio of Infected and the congestion of area. The total area consists of three zones crowded zone, mid zone and uncrowded zone, with different infection probabilities characterized by the number of people gathered there. The time for each people to spend in the crowded zone is curtailed by 0, 2, 4, 6, 7, and 8 hours, and the time spent in mid zone is extended accordingly. This simulation showed that the number of Infected and Removed will increase rapidly if there is no reduction of the time spent in crowded zone. On the other hand, the stagnant growth of Infected can be observed when the time spent in the crowded zone is reduced to 4 hours, and the growth number of Infected will decrease and the spread of the infection will subside gradually if the time spent in the crowded zone is further cut to 2 hours. In conclusions The infection spread in Japan will be gradually contained by reducing the time spent in the crowded zone to less than 4 hours.

摘要

为了评估避免大型聚会或拥挤区域的应对策略的有效性,并预测 COVID-19 感染在日本的传播情况,我们通过在 Susceptible-Infected-Removed (SIR) 传染病模型中增加对个体是否远离拥挤区域的行为的建模,开发了一个随机传播模型。人群被分为三个部分:易感者、感染者和清除者。易感者每小时都会以一个由感染者数量和区域拥挤程度决定的概率转移到感染者状态。整个区域由三个区域组成:拥挤区、中区和非拥挤区,每个区域的感染概率由聚集在那里的人数决定。每个人在拥挤区停留的时间缩短 0、2、4、6、7 和 8 小时,相应地,在中区停留的时间延长。该模拟表明,如果不减少在拥挤区停留的时间,感染者和清除者的数量将迅速增加。另一方面,如果将在拥挤区停留的时间减少到 4 小时,感染人数将呈停滞增长,并且如果进一步将在拥挤区停留的时间减少到 2 小时,感染人数将减少,感染传播将逐渐消退。总之,通过将在拥挤区停留的时间减少到 4 小时以下,日本的感染传播将逐渐得到控制。

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