Piwowarska W, Mroczek-Czernecka D
First Department of Cardiology, AM Cracow, Poland.
Ann Clin Res. 1988;20(6):389-92.
The aim of the study was to analyze rhythm disturbances and clinical course in 18 patients aged 20-52 years with mitral valve prolapse. The patients were followed up for a mean of three years (range: 1-11 years). We analyzed clinical signs, resting ECG 24 hour ECG, exercise ECG, echocardiograms and the effects of antiarrhythmic treatment. One patient developed marked mitral incompetence. Supraventricular arrhythmias occurred in three patients and ventricular extrasystoles in all 18 patients (class I in 2, II in 6, III in 4, IV in 3, V in 3, according to Lown). Five patients required combined antiarrhythmic treatment. Course of pregnancy and births in two patients with mitral valve prolapse syndrome and class IV arrhythmias were uncomplicated for both the mothers and their babies. Great clinical variability of mitral valve prolapse syndrome ranging from an asymptomatic form to ventricular fibrillation is emphasized.
本研究的目的是分析18例年龄在20至52岁之间的二尖瓣脱垂患者的心律失常情况及临床病程。对这些患者平均随访了三年（范围：1至11年）。我们分析了临床体征、静息心电图、24小时心电图、运动心电图、超声心动图以及抗心律失常治疗的效果。1例患者出现明显的二尖瓣关闭不全。3例患者发生室上性心律失常，所有18例患者均出现室性期前收缩（根据洛恩分级，I级2例，II级6例，III级4例，IV级3例，V级3例）。5例患者需要联合抗心律失常治疗。2例患有二尖瓣脱垂综合征且心律失常为IV级的患者，其妊娠和分娩过程对母亲和婴儿均无并发症。强调了二尖瓣脱垂综合征从无症状形式到心室颤动的巨大临床变异性。
