Chai Qingqing, Shen Yunjie, Du Jiangyang, Zhu Jun, Wu Bin
Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200000, China.
School of Medicine, Shanghai Jiao Tong University, Shanghai 200000, China.
Immunotherapy. 2020 Mar;12(4):245-254. doi: 10.2217/imt-2020-0030. Epub 2020 Mar 19.
As new treatment patterns are gradually being used in patients with non-small-cell lung cancer, it is necessary to have a better understanding of real-world data on clinical practices and their potential impact on healthcare resource utilization (HCRU). A retrospective observational study was conducted with electronic medical records from Shanghai Chest Hospital. Hospitalized patients treated with nivolumab or second-line chemotherapy were included. A total of 296 patients were included in this study, of whom 187 were treated with nivolumab. About 74.33% received nivolumab monotherapy at different doses. The mean cost of nivolumab was $3334.14 (±86.69). Nivolumab decreased inpatient days to 1.9545 days with a more stable cost and HCRU per cycle. Nivolumab is expensive but it reduces other HCRU.
随着新的治疗模式逐渐应用于非小细胞肺癌患者,有必要更好地了解临床实践中的真实世界数据及其对医疗资源利用(HCRU)的潜在影响。我们利用上海胸科医院的电子病历进行了一项回顾性观察研究。纳入接受纳武单抗或二线化疗的住院患者。本研究共纳入296例患者,其中187例接受纳武单抗治疗。约74.33%的患者接受了不同剂量的纳武单抗单药治疗。纳武单抗的平均费用为3334.14美元(±86.69)。纳武单抗将住院天数减少至1.9545天,每个周期的费用和医疗资源利用更为稳定。纳武单抗价格昂贵,但它减少了其他医疗资源利用。