9-(2,3-二羟基丙基)腺嘌呤和3-(腺嘌呤-9-基)-2-羟基丙酸2-甲基丙酯对马铃薯X病毒复制的抑制作用
Inhibitory effects of 9-(2,3-dihydroxypropyl)adenine and 3-(adenin-9-yl)-2-hydroxypropanoic acid 2-methylpropylester on potato virus X replication.
作者信息
Schuster G, Holý A
机构信息
Department of Life Sciences, Karl-Marx-University, Leipzig, G.D.R.
出版信息
Antiviral Res. 1988 Aug;9(5):329-34. doi: 10.1016/0166-3542(88)90027-7.
PMID:3218979
Abstract
9-(2,3-Dihydroxypropyl)adenine (DHPA) and 3-(adenin-9-yl)-2-hydroxypropanoic acid 2-methylpropylester (AHPA-MP)) markedly inhibit the replication of potato virus X (PVX). The latter compound inhibits virus replication more effectively at the lower concentration range. In synchronized virus-infected leaf-disks, the time-response course of inhibition by both compounds is almost identical, and similar to that of cycloheximide.
摘要
9-(2,3-二羟基丙基)腺嘌呤（DHPA）和3-(腺嘌呤-9-基)-2-羟基丙酸2-甲基丙酯（AHPA-MP）能显著抑制马铃薯X病毒（PVX）的复制。后一种化合物在较低浓度范围内对病毒复制的抑制作用更有效。在同步感染病毒的叶盘中，这两种化合物的抑制时间反应过程几乎相同，且与环己酰亚胺的过程相似。
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