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传染性单核细胞增多症非典型表现的细针穿刺细胞学特征

Fine needle cytology features of an atypical presentation of infectious mononucleosis.

作者信息

Gerber-Mora Roberto, Y Lillo Verónica Peña, Moreno-Silva Ricardo, González-Arriagada Wilfredo

机构信息

Medicina Bucal y Maxilofacial, Latin University of Costa Rica, San José, Costa Rica.

Department of Oral Pathology and Diagnosis, Faculty of Dentistry, Universidad de Valparaíso, Valparaíso, Chile.

出版信息

J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S139-S142. doi: 10.4103/jomfp.JOMFP_80_17. Epub 2020 Feb 28.

DOI:10.4103/jomfp.JOMFP_80_17
PMID:32189923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7069135/
Abstract

Infectious mononucleosis (IM) is a very common disease, and although in most instances, the patient develops an asymptomatic infection, other patients progress into an array of signs and symptoms that tend to be characteristic of the pathological process, guiding the clinician into choosing the right laboratory examinations under the suspicion of this illness. The most common symptoms are pharyngitis, lymphadenopathies and pyrexia, and the probabilities to develop this mononucleosis triad become greater with age. In other instances, IM can be a challenging disease to diagnose, mainly because the patient debuts with unusual symptoms such as nausea, skin eruptions, diarrhea and epigastric discomfort. The aim of the present article is to report the case of a 21-year-old female with a reactivation of IM, developing only multiple, asymptomatic lymph node enlargements in the head and neck region, showing no other sign or symptom.

摘要

传染性单核细胞增多症(IM)是一种非常常见的疾病,虽然在大多数情况下,患者会发生无症状感染,但其他患者会出现一系列往往是病理过程特征性的体征和症状,这有助于临床医生在怀疑患有此病时选择正确的实验室检查。最常见的症状是咽炎、淋巴结病和发热,随着年龄增长出现这种单核细胞增多症三联征的可能性会更大。在其他情况下,IM可能是一种难以诊断的疾病,主要是因为患者最初出现的症状不寻常,如恶心、皮疹、腹泻和上腹部不适。本文的目的是报告一例21岁女性IM复发的病例,该患者仅在头颈部出现多个无症状淋巴结肿大,无其他体征或症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d659/7069135/eeba4801e225/JOMFP-24-139-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d659/7069135/ea587c3d7333/JOMFP-24-139-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d659/7069135/7ada75d8bc1d/JOMFP-24-139-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d659/7069135/eeba4801e225/JOMFP-24-139-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d659/7069135/ea587c3d7333/JOMFP-24-139-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d659/7069135/7ada75d8bc1d/JOMFP-24-139-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d659/7069135/eeba4801e225/JOMFP-24-139-g003.jpg

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Epstein-Barr virus and its association with disease - a review of relevance to general practice.爱泼斯坦-巴尔病毒及其与疾病的关联——一篇与全科医学相关的综述。
BMC Fam Pract. 2019 May 14;20(1):62. doi: 10.1186/s12875-019-0954-3.
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Revisiting the Tissue Microenvironment of Infectious Mononucleosis: Identification of EBV Infection in T Cells and Deep Characterization of Immune Profiles.重新审视传染性单核细胞增多症的组织微环境:T 细胞中的 EBV 感染鉴定及免疫特征的深度剖析。
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由爱泼斯坦-巴尔病毒或巨细胞病毒引起的传染性单核细胞增多症的临床鉴别:日本一项单中心病例对照研究。
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Does This Patient Have Infectious Mononucleosis?: The Rational Clinical Examination Systematic Review.这患者是否患有传染性单核细胞增多症?:系统评价的合理临床检查。
JAMA. 2016 Apr 12;315(14):1502-9. doi: 10.1001/jama.2016.2111.
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Acute Epstein-Barr virus infection presenting as severe gastroenteritis without infectious mononucleosis-like manifestations.以严重肠胃炎为表现的急性爱泼斯坦-巴尔病毒感染,无传染性单核细胞增多症样表现。
Clin J Gastroenterol. 2009 Dec;2(6):398-403. doi: 10.1007/s12328-009-0114-8. Epub 2009 Oct 6.
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Infectious mononucleosis.传染性单核细胞增多症
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