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[位于下丘脑 - 垂体区域的人类肿瘤中大脑皮质神经元树突超微结构的变化]

[Changes in the dendrite ultrastructure of the cerebral cortex neurons in human tumors located in the hypothalamo-hypophyseal area].

作者信息

Kaganovskaia E A

出版信息

Arkh Anat Gistol Embriol. 1988 Sep;95(9):5-11.

PMID:3219073
Abstract

By means of electron microscopy method of bioptic material structure of the neuronal islets of the cerebral cortex has been studied in 5 persons with benign tumors that immediately effect the hypothalamus. Certain changes in ultrastructure of dendrites are revealed according to the light and dark types, as well as axons, degenerating according to the dark type. The greatest changes, including degeneration according to the dark type, undergo small branches of the dendrites. Similar pictures reflect, evidently, reduction of the dendritic tree in slightly changed cortical neurons, connected with breaking of trophic influences in the hypothalamus, evoked in it by the tumor.

摘要

通过电子显微镜方法,对5例患有直接影响下丘脑的良性肿瘤患者大脑皮质神经元胰岛的活检材料结构进行了研究。根据明暗类型揭示了树突超微结构的某些变化,以及轴突,轴突按暗型发生退化。树突的小分支发生了最大的变化,包括按暗型退化。显然,类似的情况反映了轻度改变的皮质神经元中树突树的减少,这与肿瘤引起的下丘脑中营养影响的中断有关。

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