基于1915例尸检数据的大肠腺瘤形态统计学特征

[Morphostatistical characteristics of adenomas of the large intestine based on the data from 1915 autopsies].

作者信息

Fedorov V D, Kapuller L L, Zhuravlev N V

出版信息

Arkh Patol. 1988;50(10):37-42.

PMID:3219086

Abstract

Large intestine polyps have been revealed in 1372 cases of 1915 autopsies. 4.1% of these have been hyperplastic polyps, 86.2% tubular adenomas, 11.1% tubular-villous and 2.7% villous adenomas. Solitary adenomas have been less frequent than multiple one (42 vs. 58%). The adenomas have been equally incident in the right and left portions of the large intestine, but they have been larger and characterized by a higher degree of epithelial dysplasia in the sigmoid and rectum. Malignant adenomas made up 0.8% of the total number of tumors. Adenomas have been revealed twice more frequently in the patients who died in hospital than in the group of forensic medical autopsies. Multifactorial analysis has demonstrated a correlation between adenoma detection rate and some chronic diseases.

摘要

在1915例尸检中，有1372例发现大肠息肉。其中增生性息肉占4.1%，管状腺瘤占86.2%，管状绒毛状腺瘤占11.1%，绒毛状腺瘤占2.7%。单发腺瘤的发生率低于多发腺瘤（42%对58%）。腺瘤在大肠左右部分的发生率相同，但在乙状结肠和直肠中更大，且上皮发育异常程度更高。恶性腺瘤占肿瘤总数的0.8%。在医院死亡患者中发现腺瘤的频率是法医尸检组的两倍。多因素分析表明腺瘤检出率与某些慢性疾病之间存在相关性。