Radiology Department, National Cancer Institute Pascale Foundation, via M. Semmola 53, I-80131Naples Italy.
1Motor Science and Wellness Department, University of Naples "Parthenope", via F. Acton 38, I-80133 Naples, Italy 2Advanced Biomedical Sciences Department, University Federico II of Naples (UNINA), via S. Pansini 5, I-80131 Naples Italy.
Acta Biomed. 2020 Mar 19;91(1):122-127. doi: 10.23750/abm.v91i1.8510.
Neuroma, also known as traumatic neuroma or amputation neuroma or stump neuroma, is a focal non neoplastic area of proliferative hyperplastic reaction secondary to peripheral nerve damage that commonly occurs after a focal trauma (acute or chronic) or surgery, such as amputation or partial transection. Neuromas are more commonly located in the lower limbs, followed by head and neck; other extremely rare sites include the ulnar nerve followed by the radial nerve and the brachial plexus. A radiologic plan is necessary to recognize soft tissue lesions with a neural origin and whether they are a true tumor or a pseudotumor such as a neuroma, fibrolipoma, or peripheral nerve sheath ganglion. In oncologic patients the appearance of post-surgical neuromas can produce problems in differential diagnosis with local recurrences. Therefore, with a combination of different imaging techniques, mainly ultrasound (US) and magnetic resonance imaging (MRI), it is possible to characterize neurogenic tumours safely, with a great impact on patient management and to plan an appropriate treatment. Here, we report the first case of post-amputation neuroma of radial nerve in a patient with clinical history of ephitelioid sarcoma with a short literature review.
神经瘤，又称创伤性神经瘤或截肢后神经瘤或残端神经瘤，是一种继发于周围神经损伤的局灶性非肿瘤性增生性反应区，常见于局灶性创伤（急性或慢性）或手术后，如截肢或部分横断。神经瘤更常见于下肢，其次是头颈部；其他极罕见的部位包括尺神经，其次是桡神经和臂丛。需要进行影像学检查才能识别具有神经起源的软组织病变，以及它们是真正的肿瘤还是假性肿瘤，如神经瘤、纤维脂肪瘤或周围神经鞘节细胞瘤。在肿瘤患者中，手术后神经瘤的出现可能会导致与局部复发的鉴别诊断出现问题。因此，结合不同的成像技术，主要是超声（US）和磁共振成像（MRI），可以安全地对神经源性肿瘤进行特征描述，对患者的管理和计划适当的治疗有很大的影响。在这里，我们报告了首例桡神经截肢后神经瘤的病例，该患者有上皮样肉瘤的临床病史，并对文献进行了简短回顾。
