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[2019年冠状病毒病疫情下的结直肠癌化疗策略]

[Chemotherapy strategy for colorectal cancer under the outbreak of corona virus disease 2019].

作者信息

Li Y H, Shen L, Li J

机构信息

Department of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Bejing 100142, China.

出版信息

Zhonghua Wei Chang Wai Ke Za Zhi. 2020 Mar 25;23(3):217-219. doi: 10.3760/cma.j.cn.441530-20200225-00089.

Abstract

The outbreak of corona virus disease 2019 (COVID-19) makes the medical treatment of colorectal cancers difficult. Cancer patients are more susceptible to infection and tumor history is defined as an important factor of poor prognosis, which challenges both doctors and patients. For metastatic colorectal cancer (CRC) patients, maintenance therapy is the optimal choice. The patients with tumor progression or poor biological behavior should receive or continue combination chemotherapy. Adjuvant chemotherapy should reduce the intensity of treatment and shorten the therapy time. Fever patients during chemotherapy need to receive differential diagnosis and screening according to national standards. Patients with stable diseases and good general conditions may delay imaging examination. Clinicians should make individual clinical decisions based on the specifics of each patient during epidemic situation.

摘要

2019年冠状病毒病(COVID-19)的爆发给结直肠癌的医疗带来了困难。癌症患者更容易受到感染,肿瘤病史被认为是预后不良的一个重要因素,这对医生和患者都是挑战。对于转移性结直肠癌(CRC)患者,维持治疗是最佳选择。肿瘤进展或生物学行为不佳的患者应接受或继续联合化疗。辅助化疗应降低治疗强度并缩短治疗时间。化疗期间发热的患者需要按照国家标准进行鉴别诊断和筛查。病情稳定且一般状况良好的患者可延迟影像学检查。在疫情期间,临床医生应根据每个患者的具体情况做出个体化的临床决策。

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