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对瘟疫的法医学评估——一种具有生物战潜力的再现传染病。

A forensic evaluation of plague - a re-emerging infectious disease with biowarfare potential.

机构信息

School of Medicine, The University of Adelaide, Australia.

出版信息

Med Sci Law. 2020 Jul;60(3):200-205. doi: 10.1177/0025802420908483. Epub 2020 Mar 19.

DOI:10.1177/0025802420908483
PMID:32192402
Abstract

Plague is an acute infectious disease caused by the gram-negative cocco-bacillus . It has been responsible for 200 million deaths throughout history with three major pandemics. There are three forms: bubonic, septicaemic and pneumonic, each carrying a significant mortality rate. The usual transmission is from fleas carried by rodents. Recently, it has been listed as one of the reemerging infectious diseases globally, with a potential use in bioterrorism. At autopsy there may be lymphadenopathy, fulminant pneumonia or diffuse interstitial pneumonitis. However any organ may be affected with myocarditis, meningitis, pharyngitis and hepatic and splenic necrosis. The lethality of plague with the resurgence in numbers of cases, development of antibiotic resistance, recent occurrence in urban areas and the lack of a vaccine make it a disease not to be missed in the mortuary.

摘要

鼠疫是一种由革兰氏阴性球菌引起的急性传染病。它在历史上造成了 2 亿人死亡,经历了三次大流行。有三种形式:腺鼠疫、败血型鼠疫和肺鼠疫,每种都有很高的死亡率。通常的传播途径是由啮齿动物携带的跳蚤。最近,它被列为全球新出现的传染病之一,具有生物恐怖主义的潜在用途。尸检时可能有淋巴结病、暴发性肺炎或弥漫性间质性肺炎。然而,任何器官都可能受到影响,包括心肌炎、脑膜炎、咽炎以及肝脾坏死。鼠疫的致死率很高,病例数量不断增加,抗生素耐药性的出现,最近在城市地区的发生以及缺乏疫苗,使得这种疾病在太平间不容忽视。

相似文献

1
A forensic evaluation of plague - a re-emerging infectious disease with biowarfare potential.对瘟疫的法医学评估——一种具有生物战潜力的再现传染病。
Med Sci Law. 2020 Jul;60(3):200-205. doi: 10.1177/0025802420908483. Epub 2020 Mar 19.
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The history of the plague and the research on the causative agent Yersinia pestis.鼠疫的历史以及对病原体鼠疫耶尔森菌的研究。
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Mortality risk factors show similar trends in modern and historic populations exposed to plague.在现代和历史上遭受鼠疫的人群中,死亡风险因素呈现出相似的趋势。
J Infect Dev Ctries. 2016 May 31;10(5):488-93. doi: 10.3855/jidc.7974.
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The plague pandemics and the discovery of the plague bacillus.鼠疫大流行与鼠疫杆菌的发现
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Yersinia pestis Orientalis in remains of ancient plague patients.古代鼠疫患者遗骸中的东方鼠疫杆菌。
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Reflections on crisis burials related to past plague epidemics.关于过去鼠疫流行时期的危机埋葬的思考。
Clin Microbiol Infect. 2012 Mar;18(3):218-23. doi: 10.1111/j.1469-0691.2012.03787.x.
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[The plague from antiquity to today and its final incursions into southern Italy].[从古代到今天的鼠疫及其对意大利南部的最后几次侵袭]
Ann Ig. 2002 Jan-Feb;14(1 Suppl 1):141-52.
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Plague: a review of its history and potential as a biological weapon.鼠疫:对其历史及作为生物武器的潜力的综述
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The natural history and incidence of Yersinia pestis and prospects for vaccination.鼠疫耶尔森菌的自然史和发病率及疫苗接种的前景。
J Med Microbiol. 2012 Jul;61(Pt 7):911-918. doi: 10.1099/jmm.0.037960-0. Epub 2012 Mar 22.
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Yersinia pestis DNA from skeletal remains from the 6(th) century AD reveals insights into Justinianic Plague.从公元 6 世纪骨骼遗骸中提取的鼠疫耶尔森氏菌 DNA 揭示了查士丁尼瘟疫的相关信息。
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引用本文的文献

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Heliyon. 2024 May 18;10(10):e31446. doi: 10.1016/j.heliyon.2024.e31446. eCollection 2024 May 30.
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and Plague: some knowns and unknowns.以及鼠疫:一些已知与未知情况。
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A new generation needle- and adjuvant-free trivalent plague vaccine utilizing adenovirus-5 nanoparticle platform.一种利用腺病毒5纳米颗粒平台的新一代无针无佐剂三价鼠疫疫苗。
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