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乳腺癌治疗17年后发生的乳房坏疽性脓皮病。

Pyoderma gangrenosum of the breast 17 years after breast cancer treatment.

作者信息

Pellegrino Samantha Ann, Cham Alvin, Pitcher Meron

机构信息

Breast and General Surgery, Western Health, Melbourne, Victoria, Australia

Breast and General Surgery, Western Health, Melbourne, Victoria, Australia.

出版信息

BMJ Case Rep. 2020 Mar 18;13(3):e232983. doi: 10.1136/bcr-2019-232983.

DOI:10.1136/bcr-2019-232983
PMID:32193178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7101032/
Abstract

We present a case of pyoderma gangrenosum (PG) affecting the breast of a 74-year-old woman, with a history of breast cancer treated with breast conserving surgery and adjuvant radiotherapy 17 years prior. She presented to the hospital with worsening breast ulceration, after a punch biopsy was performed at the site. She had surrounding cellulitis and concurrent infection to that breast which required antibiotics. The ulceration persisted even after treatment, and incisional biopsies of the area of ulceration confirmed the diagnosis of PG. Her condition was managed effectively with the use of immunosuppressive therapy, and she continued to display a good clinical response 2 months post discharge from the hospital.

摘要

我们报告一例坏疽性脓皮病(PG)累及一名74岁女性乳房的病例,该患者17年前有乳腺癌病史,接受了保乳手术及辅助放疗。她因乳房溃疡加重入院,此前在溃疡部位进行了组织块活检。她乳房周围有蜂窝织炎且并发感染,需要使用抗生素治疗。即使经过治疗,溃疡仍持续存在,溃疡部位的切开活检确诊为PG。通过使用免疫抑制疗法,她的病情得到了有效控制,出院2个月后仍保持良好的临床反应。

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本文引用的文献

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Pyoderma gangrenosum of the breast.乳房坏疽性脓皮病
BMJ Case Rep. 2018 Dec 22;11(1):e228243. doi: 10.1136/bcr-2018-228243.
2
Pyoderma gangrenosum: a review of pathogenesis and treatment.坏疽性脓皮病:发病机制与治疗的综述。
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Pyoderma Gangrenosum of the breast: A case report study.乳房坏疽性脓皮病:一项病例报告研究。
Int J Surg Case Rep. 2017;31:203-205. doi: 10.1016/j.ijscr.2017.01.036. Epub 2017 Jan 24.
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Acute and Chronic Cutaneous Reactions to Ionizing Radiation Therapy.电离辐射治疗的急性和慢性皮肤反应
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Pyoderma gangrenosum associated with solid organ malignancies.与实体器官恶性肿瘤相关的坏疽性脓皮病。
Int J Dermatol. 2015 Sep;54(9):e351-7. doi: 10.1111/ijd.12796. Epub 2015 Mar 13.
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Neutrophilic dermatoses: an update.中性粒细胞皮肤病:更新。
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Pyoderma gangrenosum of the breast treated with intravenous immunoglobulin.静脉注射免疫球蛋白治疗乳腺坏疽性脓皮病。
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