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自发性气胸:作为急诊科肺结核首发表现的胸腔破裂

Spontaneous Pneumothorax After Rupture of the Cavity as the Initial Presentation of Tuberculosis in the Emergency Department.

机构信息

Faculty of Medical Sciences, Guayaquil University, Guayaquil, Ecuador.

Physiology and Respiratory Center Briones-Claudett, Guayaquil, Ecuador.

出版信息

Am J Case Rep. 2020 Mar 20;21:e920393. doi: 10.12659/AJCR.920393.

Abstract

BACKGROUND Spontaneous pneumothorax can be secondary to a wide variety of lung diseases. Spontaneous pneumothorax secondary to pulmonary tuberculosis occurs in rare cases of residual fibrosis with retractions and bullae. CASE REPORT We present the case of a 65-year-old male patient from a rural area in the province of Los Ríos in Babahoyo, Ecuador, with no history of contact with tuberculosis. The patient arrived at the Emergency Department of the Regional Hospital of the Instituto Ecuatoriano de Seguridad Social (IESS), Babahoyo, due to acute respiratory failure, preceded by 10 days of evolution due to cough accompanied by greenish expectoration, chest pain, asthenia, and weight loss. On chest radiography, a left pneumothorax and interstitial pulmonary infiltrate were reported. A chest tube was placed, and the patient was intubated and was placed on invasive mechanical ventilation due to severe respiratory failure. Use of the GeneXpert MTB/RIF System detected Mycobacterium tuberculosis without resistance to rifampicin. Ziehl-Neelsen (ZN) staining for the identification of bacillus acid-resistant alcohol was positive in alveolar bronchial lavage. MALDI-TOF mass spectrometry and phenotypic analysis showed the presence of Pseudomonas aeruginosa and Klebsiella pneumonia with carbapenemases resistance mechanism, and the KPC type enzyme was identified. The culture for Mycobacterium tuberculosis was positive from the fourth week. CONCLUSIONS Secondary pneumothorax due to rupture of the polymicrobial cavity and especially of tuberculous origin is a very special form of acute respiratory failure in patients with previous structural pulmonary lesions in the Emergency Department.

摘要

背景

自发性气胸可继发于多种肺部疾病。肺结核引起的自发性气胸罕见于残余纤维化伴有回缩和大疱的情况。

病例报告

我们报告了一例来自厄瓜多尔洛斯里奥斯省巴巴奥约农村地区的 65 岁男性患者,他没有接触过结核病。患者因急性呼吸衰竭,在出现咳嗽伴绿痰、胸痛、乏力和体重减轻 10 天后,来到巴巴奥约的厄瓜多尔社会保障研究所区域医院急诊科就诊。胸部 X 线片显示左侧气胸和间质性肺部浸润。放置了胸腔引流管,由于严重呼吸衰竭,患者插管并接受有创机械通气。GeneXpert MTB/RIF 系统检测到无利福平耐药的结核分枝杆菌。肺泡支气管灌洗中抗酸杆菌的 Ziehl-Neelsen(ZN)染色呈阳性。MALDI-TOF 质谱和表型分析显示存在铜绿假单胞菌和产酸克雷伯菌,具有碳青霉烯酶耐药机制,鉴定出 KPC 型酶。第四周时结核分枝杆菌培养阳性。

结论

多微生物空洞破裂引起的继发性气胸,特别是结核性起源,是急诊科有先前结构性肺部病变的患者发生急性呼吸衰竭的一种非常特殊的形式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9476/7117856/2d26fe15fbb9/amjcaserep-21-e920393-g001.jpg

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