Liu Peng, Hu Zhicheng, Huang Shaobin, Wang Peng, Dong Yunxian, Cheng Pu, Xu Hailin, Tang Bing, Zhu Jiayuan
Department of Burn Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Department of Burn and Plastic Surgery, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou, China.
Front Bioeng Biotechnol. 2020 Mar 3;8:115. doi: 10.3389/fbioe.2020.00115. eCollection 2020.
Complex hypertrophic scar is a condition that causes multiple joint contractures and deformities after trauma or burn injuries. Three-dimensional (3D) printing technology provides a new evaluation method for this condition. The objective of this study was to print individualized 3D models of complex hypertrophic scars and to assess the accuracy of these models.
Twelve patients with complex hypertrophic scars were included in this study. Before surgery, each patient underwent a computed tomography (CT) scan to obtain cross-sectional information for 3D printing. Mimics software was used to process the CT data and create 3D printed models. The length, width, height, and volume measurements of the physical scars and 3D printed models were compared. Experienced surgeons used the 3D models to plan the operation and simulate the surgical procedure. The hypertrophic scar was completely removed for each patient and covered with skin autografts. The surgical time, bleeding, complications, and skin autograft take rate were recorded. All patients were followed up at 12 months. The surgeons, young doctors, medical students, and patients involved in the study completed questionnaires to assess the use of the 3D printed models.
The 3D models of the hypertrophic scars were printed successfully. The length, width, height, and volume measurements were significantly smaller for the 3D printed models than for the physical hypertrophic scars. Based on preoperative simulations with the 3D printed models, the surgeries were performed successfully and each hypertrophic scar was completely removed. The surgery time was shortened and the bleeding was decreased. On postoperative day 7, there were two cases of subcutaneous hemorrhage, one case of infection and one case of necrosis. On postoperative day 12, the average take rate of the skin autografts was 97.75%. At the 12-month follow-up, all patients were satisfied with the appearance and function.
Accurate 3D printed models can help surgeons plan and perform successful operations, help young doctors and medical students learn surgical methods, and enhance patient comprehension and confidence in their surgeons.
复杂性增生性瘢痕是一种在创伤或烧伤后导致多个关节挛缩和畸形的病症。三维（3D）打印技术为这种病症提供了一种新的评估方法。本研究的目的是打印复杂性增生性瘢痕的个体化3D模型，并评估这些模型的准确性。
本研究纳入了12例复杂性增生性瘢痕患者。手术前，每位患者均接受计算机断层扫描（CT）以获取用于3D打印的横断面信息。使用Mimics软件处理CT数据并创建3D打印模型。比较了实体瘢痕和3D打印模型的长度、宽度、高度和体积测量值。经验丰富的外科医生使用3D模型来规划手术并模拟手术过程。为每位患者彻底切除增生性瘢痕并用自体皮覆盖。记录手术时间、出血量、并发症和自体皮成活率。所有患者均在12个月时进行随访。参与研究的外科医生、年轻医生、医学生和患者完成了问卷调查以评估3D打印模型的使用情况。
成功打印出增生性瘢痕的3D模型。3D打印模型的长度、宽度、高度和体积测量值明显小于实体增生性瘢痕。基于使用3D打印模型进行的术前模拟，手术成功进行，每个增生性瘢痕均被彻底切除。手术时间缩短，出血量减少。术后第7天，有2例皮下出血、1例感染和1例坏死。术后第12天，自体皮的平均成活率为97.75%。在12个月的随访中，所有患者对外观和功能均满意。
精确的3D打印模型可帮助外科医生规划并成功实施手术，帮助年轻医生和医学生学习手术方法，并增强患者对其外科医生的理解和信心。
