Cusick E L, McIntosh C A, Krukowski Z H, Matheson N A
Department of Surgery, University of Aberdeen, UK.
Br J Surg. 1988 Oct;75(10):982-3. doi: 10.1002/bjs.1800751013.
During a 6-year prospective study of clinically isolated thyroid swellings (ITS), 148 (37 per cent) of 395 swellings were cystic as defined by the aspiration of fluid during fine needle aspiration cytology (FNAC). In the 106 (72 per cent) patients operated upon, 47 per cent of the cystic swellings were neoplastic and 14 per cent were malignant. In men 29 per cent of cystic swellings were malignant and 11 per cent in women. Only twelve cystic ITS were permanently abolished by aspiration and FNAC was inaccurate in predicting neoplasia. The incidence of malignancy in cystic ITS is higher than generally accepted and most cysts not abolished by aspiration should be removed.
在一项针对临床孤立性甲状腺肿物（ITS）的6年前瞻性研究中，395个肿物中有148个（37%）在细针穿刺抽吸细胞学检查（FNAC）时通过液体抽吸确定为囊性。在接受手术的106例（72%）患者中，47%的囊性肿物为肿瘤性，14%为恶性。男性中29%的囊性肿物为恶性，女性为11%。仅12个囊性ITS通过抽吸得以永久消除，且FNAC在预测肿瘤形成方面不准确。囊性ITS中的恶性发生率高于普遍认知，大多数未通过抽吸消除的囊肿应予以切除。
